| 词条 | Folin's reagent | ||||||||||||||||||||||||||||||||
| 释义 |
| verifiedrevid = 400790361 | ImageFile=Folin's Reagent Structural Formula V1.svg | ImageSize=200 | ImageAlt=Skeletal formula of Folin's reagent | ImageFile1=Folin's reagent 3D spacefill.png | ImageSize1=160 | ImageAlt1=Space-filling model of the Folin's reagent molecule | IUPACName=Sodium 3,4-dioxo-3,4-dihydronaphthalene-1-sulfonate | OtherNames= |Section1={{Chembox Identifiers | CASNo=521-24-4 | SMILES=C1=CC=C2C(=C1)C(=CC(=O)C2=O)S(=O)(=O)[O-].[Na+] | EINECS = 208-308-9 | PubChem = 10636 | ChemSpiderID = 10190 | InChI = 1/C10H6O5S.Na/c11-8-5-9(16(13,14)15)6-3-1-2-4-7(6)10(8)12;/h1-5H,(H,13,14,15);/q;+1/p-1 | InChIKey = UBLXEEBHYISRFM-REWHXWOFAQ | StdInChI = 1S/C10H6O5S.Na/c11-8-5-9(16(13,14)15)6-3-1-2-4-7(6)10(8)12;/h1-5H,(H,13,14,15);/q;+1/p-1 | StdInChIKey = UBLXEEBHYISRFM-UHFFFAOYSA-M |Section2={{Chembox Properties | Formula=C10H5NaO5S | MolarMass=260.20 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | ExternalSDS = Oxford MSDS | FlashPt= | AutoignitionPt = }}Folin's reagent or sodium 1,2-naphthoquinone-4-sulfonate is a chemical reagent used as a derivatizing agent to measure levels of amines and amino acids.[1] The reagent reacts with them in alkaline solution to produce a fluorescent material that can be easily detected.[2] This should not be confused with Folin-Ciocalteu reagent, that is used to detect phenolic compounds. The Folin reagent can be used with an acidic secondary reagent to distinguish MDMA and related compounds from PMMA and related compounds.[3]{{Failed verification|date=February 2017}}
See also
References1. ^{{cite journal |vauthors=Saurina J, Hernández-Cassou S |title=Determination of amino acids by ion-pair liquid chromatography with post-column derivatization using 1,2-naphthoquinone-4-sulfonate |journal=Journal of Chromatography A |volume=676 |issue=2 |pages=311–9 |year=1994 |pmid=7921184 |doi=10.1016/0021-9673(94)80431-1}} 2. ^{{cite journal |vauthors=Kobayashi Y, Kubo H, Kinoshita T |title=Fluorometric determination of guanidino compounds by new postcolumn derivatization system using reversed-phase ion-pair high-performance liquid chromatography |journal=Anal. Biochem. |volume=160 |issue=2 |pages=392–8 |year=1987 |pmid=3578768 |doi=10.1016/0003-2697(87)90066-2}} 3. ^1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 {{cite web | url=https://dancesafe.org/product/folin-reagent-new/ | title=Folin Reagent Testing Kit | publisher=Dancesafe | date=June 2015 | accessdate=8 August 2015}} 3 : Chemical tests|1,2-Naphthoquinones|Naphthalenesulfonates |
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