| 词条 | Frontonasal prominence |
| 释义 |
| Name = Frontonasal prominence | Latin = prominentia frontonasalis | Image = Gray44.png | Caption = Under surface of the head of a human embryo about twenty-nine days old. (Frontonasal process labeled at center left.) | Image2 = | Caption2 = | System = | CarnegieStage = | Precursor = Ectoderm | GivesRiseTo = }} During the third week of embryonic development, two areas of thickened ectoderm, the olfactory areas, appear immediately under the fore-brain in the anterior wall of the stomodeum, one on either side of a region termed the frontonasal prominence (or process). By the upgrowth of the surrounding parts these areas are converted into two nasal pits, which indent the frontonasal prominence and divide it into a medial and two lateral nasal processes. There is some evidence that development involves Sonic hedgehog and Fibroblast growth factor 8.[1] References{{Gray's}}1. ^{{cite journal |vauthors=Abzhanov A, Cordero DR, Sen J, Tabin CJ, Helms JA |title=Cross-regulatory interactions between Fgf8 and Shh in the avian frontonasal prominence |journal=Congenit Anom (Kyoto) |volume=47 |issue=4 |pages=136–48 |date=December 2007 |pmid=17988255 |doi=10.1111/j.1741-4520.2007.00162.x}} External links
1 : Embryology |
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