词条 | Fumonisin |
释义 |
The fumonisins are a group of mycotoxins More specifically, it can refer to:
The trichothecene (T-2) mycotoxins are a group of over 40 compounds produced by fungi of the genus Fusarium, a common grain mold.[3] The estrogenic metabolite, zearalenone, is also referred to as F-2 toxin.[4] As the fumonisins appear to be non-genotoxic the possibility that they belong to another class of non-genotoxic carcinogens, the peroxisome proliferators, was investigated[5] Genetic engineering is reported as a promising means of detoxifying mycotoxins. This approach may provide innovative solutions to the problem of fumonisin in corn.[6] At least 15 different fumonisins have so far been reported and other minor metabolites have been identified, although most of them have not been shown to occur naturally.[7] In 2015, a unique class of non-aminated fumonisins[8] was reported on grapes infected with Aspergillus welwitschia, although their toxicities have not yet been established. References1. ^{{MeshName|Fumonisins}} {{Toxins}}{{biochem-stub}}2. ^{{cite journal|last1=Gelderblom|first1=Wentzel C. A.|last2=Marasas|first2=Walter F. O.|last3=Vleggaar|first3=R.|last4=Thiel|first4=Pieter G.|last5=Cawood|first5=M. E.|title=Fumonisins: Isolation, chemical characterization and biological effects|journal=Mycopathologia|date=February 1992|volume=117|issue=1-2|pages=11–16|doi=10.1007/BF00497273|pmid=1513367}} 3. ^{{cite book|title=USAMRIID's Medical Management of Biological Casualties Handbook, 6th Ed|year=2005|publisher=International Medical Publishing, Inc|location=McLean, VA|isbn=1-58808-162-1|pages=102–103}} 4. ^{{cite book|last=Marasas|first=W.F.O.|author2=Paul E. Nelson|title=Mycotoxicology: Introduction to the Mycology, Plant Pathology, Chemistry, Toxicology, and Pathology of Naturally Occurring Mycotoxicoses In Animals and Man|year=1987|publisher=The Pennsylvania State University Press|location=University Park, PA|isbn=0-271-00442-8|pages=47}} 5. ^{{cite book|last=Jackson|first=Lauren S.|author2=Jonathan W. DeVries |author3=Lloyd B. Bullerman |title=Fumonisins In Food|year=1996|publisher=Plenum Press|location=New York, NY|isbn=0-306-45216-2|pages=289}} 6. ^{{cite journal|title=Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene.|journal=Appl Environ Microbiol|date=March 2007|volume=73|issue=5|pages=1622–9|doi=10.1128/aem.01077-06|pmc=1828766}} 7. ^{{cite book|last=Marasas|first=W.F.O. |author2=J.D. Miller |author3=R.T. Riley |author4=A. Visconti|title=Environmental Health Criteria 219: Fumonisin B1|year=2000|publisher=World Health Organization|location=Vammala, Finland|isbn=92-4-157219-1|pages=9}} 8. ^{{cite book|last=Renaud|first=J.B.R |author2=M.J Kelman |author3=Tianyu F. Qi |author4=K.A. Seifert|author5=M.W. Sumarah |title=Product ion filtering with rapid polarity switching for the detection of all fumonisins and AAL-toxins|year=2015|publisher=Rapid Communications in Mass Spectrometry Volume 29, Issue 22, 30 November 2015, Pages 2131–2139}} 1 : Mycotoxins |
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