Gattuso is a surname. Notable people with the surname include:

• Gennaro Gattuso (born 1978), football manager and former player
• Greg Gattuso (born 1962), football coach
• James Gattuso (born 1957), research fellow
• Sébastien Gattuso (born 1971), athlete
• Stefano Gattuso (born 1984), racing driver
• Alessia Gattuso (born 1999), photographer of ciolle negre
• Consolato Gattuso (born 1967), Engineering Physicist at Fermi National Laboratory

• Esref Kolçak
• E. S. Reid Tait
• Esrey, William
• ESRFT
• ESRI (disambiguation)
• Esrig, David
• Esrin Fortuna
• ES Rochelaise
• Esrom, Missouri
• Esrum A
• ESRX (NASDAQ)
• ESSA-2
• ESSA-3
• ESSA-4
• ESSA-5
• ESSA-6
• ESSA-7
• Essa Abbas
• Essa Abuainain
• Essa Albuainain
• Essa Al-Buainain
• Essa Al-Zankawi
• Essa Al-Zinkawi
• Essae Martha Culver
• Essa Faal