“GDP-6-deoxy-D-talose 4-dehydrogenase”的意思、由来-开放百科全书

词条

GDP-6-deoxy-D-talose 4-dehydrogenase

释义

References

{{enzyme
| Name = GDP-6-deoxy-D-talose 4-dehydrogenase
| EC_number = 1.1.1.135
| CAS_number = 37250-66-1
| IUBMB_EC_number = 1/1/1/135
| GO_code = 0047916
| image =
| width =
| caption =
}}

In enzymology, a GDP-6-deoxy-D-talose 4-dehydrogenase ({{EC number|1.1.1.135}}) is an enzyme that catalyzes the chemical reaction

GDP-6-deoxy-D-talose + NAD(P)+ GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H⁺

The 3 substrates of this enzyme are GDP-6-deoxy-D-talose, NAD⁺, and NADP⁺, whereas its 4 products are GDP-4-dehydro-6-deoxy-D-mannose, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is GDP-6-deoxy-D-talose:NAD(P)⁺ 4-oxidoreductase. This enzyme is also called guanosine diphospho-6-deoxy-D-talose dehydrogenase. This enzyme participates in fructose and mannose metabolism.

References

{{cite journal | author = Markovitz A | year = 1964 | title = Biosynthesis of guanosine diphosphate D-rhamnose and guanosine diphosphate D-talomethylose from guanosine diphosphate alpha-D-mannose | journal = J. Biol. Chem. | volume = 239 | pages = 2091–2098 | pmid=14209931}}

4 : EC 1.1.1|NADPH-dependent enzymes|NADH-dependent enzymes|Enzymes of unknown structure

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