“Geissoschizine dehydrogenase”的意思、由来-开放百科全书

词条

Geissoschizine dehydrogenase

释义

References

{{enzyme
| Name = geissoschizine dehydrogenase
| EC_number = 1.3.1.36
| CAS_number = 84399-94-0
| IUBMB_EC_number = 1/3/1/36
| GO_code = 0047920
| image =
| width =
| caption =
}}

In enzymology, a geissoschizine dehydrogenase ({{EC number|1.3.1.36}}) is an enzyme that catalyzes the chemical reaction

geissoschizine + NADP⁺ 4,21-didehydrogeissoschizine + NADPH

Thus, the two substrates of this enzyme are geissoschizine and NADP⁺, whereas its two products are 4,21-didehydrogeissoschizine and NADPH.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is geissoschizine:NADP+ 4,21-oxidoreductase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

References

{{cite journal |vauthors=Pfitzner A, Stockigt J| date = 1982 | title = Partial-purification and characterization of geissoschizine dehydrogenase from suspension-cultures of Catharanthus roseus | journal = Phytochemistry | volume = 21 | pages = 1585–1588 | doi=10.1016/s0031-9422(82)85022-x}}

3 : EC 1.3.1|NADPH-dependent enzymes|Enzymes of unknown structure

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