George Pepper may refer to:

• George Pepper (film producer) (1913–1969), American film producer, Hollywood organizer, child violin prodigy
• George W. Pepper (1867–1961), American lawyer, law professor, and Republican politician from Pennsylvania
• George H. Pepper (1873–1924), American ethnologist and archaeologist
• George Pepper (artist) (1903–1962), Canadian artist

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