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词条 Glucogenic amino acid
释义

  1. See also

  2. References

  3. External links

A glucogenic amino acid is an amino acid that can be converted into glucose through gluconeogenesis.[1] This is in contrast to the ketogenic amino acids, which are converted into ketone bodies.

The production of glucose from glucogenic amino acids involves these amino acids being converted to alpha keto acids and then to glucose, with both processes occurring in the liver. This mechanism predominates during catabolysis, rising as fasting and starvation increase in severity.

In humans, the glucogenic amino acids are:

  • Alanine
  • Arginine
  • Asparagine
  • Aspartic acid
  • Cysteine
  • Glutamic acid
  • Glutamine
  • Glycine
  • Histidine
  • Methionine
  • Proline
  • Serine
  • Valine

Amino acids that are both glucogenic and ketogenic (mnemonic "PITTT"):

  • Phenylalanine
  • Isoleucine
  • Threonine
  • Tryptophan
  • Tyrosine

Only leucine and lysine are not glucogenic (they are only ketogenic).

See also

  • Glycolysis
  • List of standard amino acids
  • Metabolism

References

1. ^*{{cite journal |author=Brosnan J |title=Interorgan amino acid transport and its regulation |url=http://jn.nutrition.org/cgi/content/full/133/6/2068S |journal=J Nutr |volume=133 |issue=6 Suppl 1 |pages=2068S–2072S |date=1 June 2003|pmid=12771367 }}*{{cite journal |author=Young V, Ajami A |title=Glutamine: the emperor or his clothes? |url=http://jn.nutrition.org/cgi/content/full/131/9/2449S |journal=J Nutr |volume=131 |issue=9 Suppl |pages=2449S–59S; discussion 2486S–7S |date=1 September 2001|pmid=11533293 }}

External links

  • Amino acid metabolism
  • [https://web.archive.org/web/20070630191421/http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=stryer.chapter.3193 Chapter on Amino acid catabolism in Biochemistry] by Jeremy Berg, John Tymoczko, Lubert Stryer. Fourth ed. by Lubert Stryer. {{ISBN|0-7167-4955-6}} Accessed 2007-03-17
  • [https://web.archive.org/web/20050125113703/http://www.dentistry.leeds.ac.uk/biochem/thcme/aminoacidmetabolism.pdf Amino acid metabolism]
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4 : Amino acids|Glucogenic amino acids|Nitrogen cycle|Medical mnemonics

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