“Glucose-6-phosphate 1-epimerase”的意思、由来-开放百科全书

词条

Glucose-6-phosphate 1-epimerase

释义

Structural studies
References

{{enzyme
| Name = glucose-6-phosphate 1-epimerase
| EC_number = 5.1.3.15
| CAS_number = 37259-65-7
| IUBMB_EC_number = 5/1/3/15
| GO_code = 0047938
| image =
| width =
| caption =
}}

In enzymology, a glucose-6-phosphate 1-epimerase ({{EC number|5.1.3.15}}) is an enzyme that catalyzes the chemical reaction

alpha-D-glucose 6-phosphate beta-D-glucose 6-phosphate

Hence, this enzyme has one substrate, alpha-D-glucose 6-phosphate, and one product, beta-D-glucose 6-phosphate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is D-glucose-6-phosphate 1-epimerase. This enzyme participates in glycolysis / gluconeogenesis.

Structural studies

As of late 2013, 3 structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|2CIQ}}, {{PDB link|2CIR}}, and {{PDB link|2CIS}}.

References

{{cite journal | vauthors = Wurster B, Hess B | date = 1972 | title = Glucose-6-phosphate-1-epimerase from baker's yeast. A new enzyme | journal = FEBS Lett. | volume = 23 | pages = 341–344 | pmid = 11946648 | doi = 10.1016/0014-5793(72)80311-9 | issue = 3 }}

2 : EC 5.1.3|Enzymes of known structure

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