“Glutarate-semialdehyde dehydrogenase”的意思、由来-开放百科全书

词条

Glutarate-semialdehyde dehydrogenase

释义

References

{{enzyme
| Name = glutarate-semialdehyde dehydrogenase
| EC_number = 1.2.1.20
| CAS_number = 9028-99-3
| IUBMB_EC_number = 1/2/1/20
| GO_code = 0047949
| image =
| width =
| caption =
}}

In enzymology, a glutarate-semialdehyde dehydrogenase ({{EC number|1.2.1.20}}) is an enzyme that catalyzes the chemical reaction

glutarate semialdehyde + NAD⁺ + H₂O glutarate + NADH + 2 H⁺

The 3 substrates of this enzyme are glutarate semialdehyde, NAD⁺, and H₂O, whereas its 3 products are glutarate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glutarate-semialdehyde:NAD+ oxidoreductase. This enzyme is also called glutarate semialdehyde dehydrogenase. This enzyme participates in lysine degradation.

References

{{cite journal |author1 = Ichihara A |author2 =Ichihara EA | location = Tokyo | title = Metabolism of L-lysine by bacterial enzymes. V. Glutaric semialdehyde dehydrogenase | journal = J. Biochem. | volume = 49| pages = 154–157 | pmid=13717359 | date=February 1961}}

3 : EC 1.2.1|NADH-dependent enzymes|Enzymes of unknown structure

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