“Glyoxylate dehydrogenase (acylating)”的意思、由来-开放百科全书

词条

Glyoxylate dehydrogenase (acylating)

释义

References

{{enzyme
| Name = glyoxylate dehydrogenase (acylating)
| EC_number = 1.2.1.17
| CAS_number = 9028-96-0
| IUBMB_EC_number = 1/2/1/17
| GO_code = 0047968
| image =
| width =
| caption =
}}

In enzymology, a glyoxylate dehydrogenase (acylating) ({{EC number|1.2.1.17}}) is an enzyme that catalyzes the chemical reaction

glyoxylate + CoA + NADP⁺ oxalyl-CoA + NADPH + H⁺

The 3 substrates of this enzyme are glyoxylate, CoA, and NADP⁺, whereas its 3 products are oxalyl-CoA, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glyoxylate:NADP+ oxidoreductase (CoA-oxalylating). This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

{{cite journal |author1 = Quayle JR |author2 =Taylor GA | date = 1961 | title = Carbon assimilation by Pseudomonas oxalaticus (OX1). 5. Purification and properties of glyoxylic dehydrogenase | journal = Biochem. J. | volume = 78 | pages = 611–615 }}

3 : EC 1.2.1|NADPH-dependent enzymes|Enzymes of unknown structure

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