| 词条 | GSTT1 |
| 释义 |
Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.[2] References1. ^{{cite journal |vauthors=Webb G, Vaska V, Coggan M, Board P | title = Chromosomal localization of the gene for the human theta class glutathione transferase (GSTT1) | journal = Genomics | volume = 33 | issue = 1 | pages = 121–3 |date=Jun 1996 | pmid = 8617495 | pmc = | doi = 10.1006/geno.1996.0167 }} {{PDB Gallery|geneid=2952}}{{gene-22-stub}}2. ^{{cite web | title = Entrez Gene: GSTT1 glutathione S-transferase theta 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2952| accessdate = }} 2 : Enzymes|Genes |
| 随便看 |
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。