| 词条 | Hairy RNA localisation element (HLE) |
| 释义 |
| Name = Hairy RNA localisation element (HLE) | image = RF00437.jpg | width = | caption = Predicted secondary structure and sequence conservation of HLE | Symbol = HLE | AltSymbols = | Rfam = RF00437 | miRBase = | miRBase_family = | RNA_type = Cis-reg | Tax_domain = Eukaryota | GO = | SO = {{SO|0000233}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} The hairy localisation element (HLE) is an RNA element found in the 3' UTR of the hairy gene. HLE contains two stem-loops. HLE is essential for the mediation of apical localisation and the two stem-loop structures act to allow the recognition of hairy mRNA by the localisation machinery.[1] HLE is found in Drosophila species. References1. ^{{cite journal | last = Bullock | first = SL |author2=Zicha D |author3=Ish-Horowicz D | year = 2003 | title = The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport | journal = EMBO J | volume = 22 | pages = 2484–2494 | pmid = 12743042 | doi = 10.1093/emboj/cdg230 | issue = 10 | pmc = 155988}} External links
1 : Cis-regulatory RNA elements |
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