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词条 Hans Grüneberg
释义

  1. Career

  2. Books

  3. References

  4. External links

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Hans Grüneberg {{post-nominals|country=GBR|size=100%|FRS}}[1] (26 May 1907 – 23 October 1982), whose name was also written as Hans Grueneberg and Hans Gruneberg, was a British geneticist. Grüneberg was born in Wuppertal–Elberfeld in Germany. He obtained an MD from the University of Bonn, a PhD in biology from the University of Berlin and a DSc from the University of London. He arrived in London in 1933, at the invitation of J.B.S. Haldane and Sir Henry Dale.

He was elected a Fellow of the Royal Society in 1956.[1] Most of his work focused on mouse genetics,[2][3][4][5][6][7][8][9][10][11][12][13] in which his speciality was the study of pleiotropic effects of mutations on the development of the mouse skeleton.

He was the first person to describe siderocytes and sideroblasts, atypical nucleated erythrocytes with granules of iron accumulated in perinuclear mitochondria.[14] This he reported in the journal Nature.[15][16][17] The Grüneberg ganglion,[18] an olfactory ganglion in rodents, was first described by Hans Grueneberg in 1973.

Career

  • Honorary Research Assistant, University College London, 1933–38
  • Moseley Research Student of Royal Society, 1938–42
  • Captain, Royal Army Medical Corps, 1942–46
  • Reader in Genetics, University College London, 1946–55
  • Honorary Director of the Medical Research Council Experimental Genetics Unit at University College London, 1955–1972
  • Professor of Genetics University College London, 1956–1974
  • Affiliated with the Department of Pathology, Mount Vernon Hospital, Northwood, Middlesex
  • Emeritus Professor University College London, from retirement, 1974

Books

  • 1947. Animal genetics and medicine. Hamish Hamilton, London.
  • 1952. The genetics of the mouse. 2nd ed, revised and enlarged. Nijhoff, The Hague.
  • 1963. The pathology of development: a study of inherited skeletal disorders in animals. Wiley, London.

References

1. ^1 {{Cite journal | last1 = Lewis | first1 = Dan | last2 = Hunt | first2 = D. M. | doi = 10.1098/rsbm.1984.0008 | title = Hans Gruneberg. 26 May 1907 – 23 October 1982 | journal = Biographical Memoirs of Fellows of the Royal Society | volume = 30 | pages = 226 | year = 1984 | jstor = 769826| pmid = 11616003}}
2. ^{{Cite journal | last1 = Grüneberg | first1 = H. | last2 = Wickramaratne | first2 = G. A. | title = A re-examination of two skeletal mutants of the mouse, vestigial-tail (vt) and congenital hydrocephalus (ch) | journal = Journal of Embryology and Experimental Morphology | volume = 31 | issue = 1 | pages = 207–222 | year = 1974 | pmid = 4819561}}
3. ^{{Cite journal | last1 = Grüneberg | first1 = H. | last2 = Lee | first2 = A. J. | title = The anatomy and development of brachypodism in the mouse | journal = Journal of Embryology and Experimental Morphology | volume = 30 | issue = 1 | pages = 119–141 | year = 1973 | pmid = 4729943}}
4. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = Exocrine glands and the Chievitz organ of some mouse mutants | journal = Journal of Embryology and Experimental Morphology | volume = 25 | issue = 2 | pages = 247–261 | year = 1971 | pmid = 5088022}}
5. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = The glandular aspects of the tabby syndrome in the mouse | journal = Journal of Embryology and Experimental Morphology | volume = 25 | issue = 1 | pages = 1–19 | year = 1971 | pmid = 5548211}}
6. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = Threshold phenomena versus cell heredity in the manifestation of sex-linked genes in mammals | journal = Journal of Embryology and Experimental Morphology | volume = 22 | issue = 2 | pages = 145–179 | year = 1969 | pmid = 5361553}}
7. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = More about the tabby mouse and about the Lyon hypothesis | journal = Journal of Embryology and Experimental Morphology | volume = 16 | issue = 3 | pages = 569–590 | year = 1966 | pmid = 5962700}}
8. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = The molars of the tabby mouse, and a test of the 'single-active X-chromosome' hypothesis | journal = Journal of Embryology and Experimental Morphology | volume = 15 | issue = 2 | pages = 223–244 | year = 1966 | pmid = 5959976}}
9. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = Genes and genotypes affecting the teeth of the mouse | journal = Journal of Embryology and Experimental Morphology | volume = 14 | issue = 2 | pages = 137–159 | year = 1965 | pmid = 5893447}}
10. ^{{Cite journal | last1 = Gruneberg | first1 = H. | title = Genetical studies on the skeleton of the mouse. XXIII. The development of brachyury and anury | journal = Journal of Embryology and Experimental Morphology | volume = 6 | issue = 3 | pages = 424–443 | year = 1958 | pmid = 13575656}}
11. ^{{Cite journal | last1 = Gruneberg | first1 = H. | title = Genetical studies on the skeleton of the mouse. XXII. The development of Danforth's short-tail | journal = Journal of Embryology and Experimental Morphology | volume = 6 | issue = 1 | pages = 124–148 | year = 1958 | pmid = 13539275}}
12. ^{{Cite journal | last1 = Grüneberg | first1 = H. | last2 = Burnett | first2 = J. B. | last3 = Snell | first3 = G. D. | title = The Origin of Jerker, a New Gene Mutation of the House Mouse, and Linkage Studies Made with It | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 27 | issue = 12 | pages = 562–565 | year = 1941 | pmid = 16588504 | pmc = 1078382 | doi=10.1073/pnas.27.12.562| bibcode = 1941PNAS...27..562G}}
13. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = Inherited Macrocytic Anemias in the House Mouse | journal = Genetics | volume = 24 | issue = 6 | pages = 777–810 | year = 1939 | pmid = 17246952 | pmc = 1209073}}
14. ^medical-dictionary
15. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = Is there a viral component in the genetic background? | journal = Nature | volume = 225 | issue = 5227 | pages = 39–41 | year = 1970 | pmid = 5410193 | doi=10.1038/225039a0| bibcode = 1970Natur.225...39G}}
16. ^{{Cite journal | last1 = Gruneberg | first1 = H. | title = A ventral ectodermal ridge of the tail in mouse embryos | journal = Nature | volume = 177 | issue = 4513 | pages = 787–788 | year = 1956 | pmid = 13321960 | doi=10.1038/177787b0| bibcode = 1956Natur.177..787G}}
17. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = Variation Within Inbred Strains of Mice | doi = 10.1038/173674a0 | journal = Nature | volume = 173 | issue = 4406 | pages = 674–676 | year = 1954 | pmid = 13165620| bibcode = 1954Natur.173..674G }}
18. ^{{Cite journal | last1 = Grüneberg | first1 = H. | title = A ganglion probably belonging to the N. Terminalis system in the nasal mucosa of the mouse | journal = Zeitschrift für Anatomie und Entwicklungsgeschichte | volume = 140 | issue = 1 | pages = 39–52 | year = 1973 | pmid = 4749131}}

External links

  • Codebreakers: Makers of Modern Genetics: the Hans Grüneberg papers
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13 : 1907 births|1982 deaths|People from Wuppertal|German emigrants to England|British geneticists|20th-century British biologists|Royal Army Medical Corps officers|British Army personnel of World War II|Fellows of the Royal Society|Jewish scientists|Academics of University College London|20th-century British medical doctors|Jewish emigrants from Nazi Germany to the United Kingdom
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