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词条 Hexafluronium bromide
释义

  1. References

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 461767845
| IUPAC_name = N,N-di-9H-fluoren-9-yl-N,N,N',N'-tetramethylhexane-1,6-diaminium dibromide
| image = Hexafluronium bromide.svg
| width = 250px
| drug_name = Hexafluronium
| tradename =
| pregnancy_category =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|changed|CAS}}
| CAS_number = 317-52-2
| ATC_prefix = M03
| ATC_suffix = AC05
| PubChem = 9434
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB00941
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 9063
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = B64NJG83K2
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D04435
| C=36 | H=42 | Br=2 | N=2
| molecular_weight = 662.54 g/mol
| smiles = [Br-].[Br-].c1cccc3c1c2c(cccc2)C3[N+](CCCCCC[N+](C6c4ccccc4c5ccccc56)(C)C)(C)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C36H42N2.2BrH/c1-37(2,35-31-21-11-7-17-27(31)28-18-8-12-22-32(28)35)25-15-5-6-16-26-38(3,4)36-33-23-13-9-19-29(33)30-20-10-14-24-34(30)36;;/h7-14,17-24,35-36H,5-6,15-16,25-26H2,1-4H3;2*1H/q+2;;/p-2
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = WDEFPRUEZRUYNW-UHFFFAOYSA-L
}}

Hexafluronium (or hexafluorenium) is a muscle relaxant.[1] It acts as a nicotinic acetylcholine receptor antagonist.

References

1. ^{{cite journal |author=Baraka A |title=Hexafluorenium-suxamethonium interaction in patients with normal versus atypical cholinesterase |journal=Br J Anaesth |volume=47 |issue=8 |pages=885–8 |date=August 1975 |pmid=1201167 |doi= 10.1093/bja/47.8.885|url=http://bja.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=1201167}}
{{Muscle relaxants}}{{Nicotinic acetylcholine receptor modulators}}{{musculoskeletal-drug-stub}}

5 : Muscle relaxants|Bromides|Nicotinic antagonists|Quaternary ammonium compounds|Fluorenes

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