| 词条 | Hexethal |
| 释义 |
| verifiedrevid = 449583191 | IUPAC_name = sodium 5-ethyl-5-hexyl-4,6-dioxo-1H-pyrimidin-2-olate | image = Sodium_Hexethal.svg | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = Schedule IV | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 144-00-3 | ATC_prefix = none | ATC_suffix = | PubChem = 8941 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 8597 | C=12 | H=19 | N=2 | Na=1 | O=3 | molecular_weight = 262.281 g/mol | smiles = [Na+].O=C1/N=C(/[O-])NC(=O)C1(CCCCCC)CC | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = HXUAXLUDTCGASZ-UHFFFAOYSA-M | synonyms = Sodium 5-ethyl-5-hexylbarbiturate, Ortal, Hebaral }} Hexethal (Ortal) is a barbiturate derivative invented in the 1940s. It has sedative, anxiolytic, muscle relaxant, and anticonvulsant properties, and was used primarily as an anaesthetic in veterinary medicine. [1]Hexethal is considered similar in effects to pentobarbital, with a very fast onset of action but short duration of effects. References1. ^{{Cite journal | last1 = Butler | first1 = T. C. | title = The rate of penetration of barbituric acid derivatives into the brain | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 100 | issue = 2 | pages = 219–226 | year = 1950 | pmid = 14784958}} {{GABAAR PAMs}}{{sedative-stub}} 2 : Barbiturates|GABAA receptor positive allosteric modulators |
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