“Histone-arginine N-methyltransferase”的意思、由来-开放百科全书

词条

Histone-arginine N-methyltransferase

释义

References
External links

{{Infobox enzyme
| Name = Histone-arginine N-methyltransferase
| EC_number = 2.1.1.125
| CAS_number = 445295-80-7
| IUBMB_EC_number = 2/1/1/125
| GO_code =
| image =
| width =
| caption =
}}Histone-arginine N-methyltransferase ({{EC number|2.1.1.125}}, histone protein methylase I, nuclear protein (histone) N-methyltransferase, protein methylase I, S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:histone-arginine Nomega-methyltransferase.^[1]^[2] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + histone-arginine S-adenosyl-L-homocysteine + histone-Nomega-methyl-arginine

The enzyme forms the Nomega-monomethyl- and Nomega,Nomega'-dimethyl.

References

1. ^{{cite journal | vauthors = Rajpurohit R, Lee SO, Park JO, Paik WK, Kim S | title = Enzymatic methylation of recombinant heterogeneous nuclear RNP protein A1. Dual substrate specificity for S-adenosylmethionine:histone-arginine N-methyltransferase | journal = The Journal of Biological Chemistry | volume = 269 | issue = 2 | pages = 1075–82 | date = January 1994 | pmid = 8288564 }}
2. ^{{cite journal | vauthors = Rawal N, Rajpurohit R, Paik WK, Kim S | title = Purification and characterization of S-adenosylmethionine-protein-arginine N-methyltransferase from rat liver | journal = The Biochemical Journal | volume = 300 ( Pt 2) | issue = Pt 2 | pages = 483–9 | date = June 1994 | pmid = 8002954 | pmc = 1138188 }}

External links

{{MeshName|Histone-arginine+N-methyltransferase}}

1 : EC 2.1.1

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