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词条 HLA-B42
释义

  1. Serotype

     B*4201 allele frequencies 

  2. References

major histocompatibility complex (human), class I, B42
AllelesB*4201
B*4202
Structure (See HLA-B)
Symbol(s)[https://web.archive.org/web/20070821210135/http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=4932 HLA-B]
EBI-HLAB*4201
EBI-HLAB*4202
Locuschr.6 [https://www.ncbi.nlm.nih.gov/Omim/getmap.cgi?chromosome=6p21.31 6p21.31]

HLA-B42 (B42) is an HLA-B serotype. The serotype identifies the HLA-B*4201 and *4202 gene products.[1] HLA-B*4201 is common in Central Africa. (For terminology help see: HLA-serotype tutorial)

Serotype

B42 serotype recognition of Some HLA B*42 allele-group gene products[2]
B*42B42otherSample
allele % % size (N)
4201 93 2 1015
4202 95 80

Serological typing for B*4201 and B*4202 is relatively efficient.

B*4201 allele frequencies

HLA B*4201 frequencies
freq
ref. Population(%)
[3] Zambia Lusaka14.8
[3] Mali Bandiagara13.8
[3] Burkina Faso Mossi13.2
[3] South African Natal Zulu12.0
[3] Burkina Faso Rimaibe9.6
[3] South Africa Tswana8.5
[3] Kenya Luo7.7
[3] Kenya7.3
[3] Kenya Nandi6.9
[3] Zimbabwe Harare Shona6.9
[3] Saudi Arabia5.6
[3] Cameroon Yaounde4.9
[3] Cameroon Beti4.0
[3] Cameroon Bamileke3.9
[3] Cameroon Sawa3.8
[3] Ivory Coast Akan Adiopodoume3.4
[3] Israel Gaza Palestinians2.4
[3] India North Delhi2.2
[3] Senegal Niokholo Mandenka1.6
[3] Mbenzele Pygmy (C. Afr. Rep.)1.5
[3] Iran Baloch1.5
[3] Pakistan Baloch1.5
[3] Sudanese1.5
[3] Tunisia1.5
[3] Pakistan Brahui1.4
[3] Cameroon Bamileke1.3
[3] Oman1.3
[3] Sudanese1.3
[3] Tunisia Tunis1.1
[3] Zimbabwe Harare Shona1.1
[3] Cameroon Bakola Pygmy1.0
[3] Pakistan Pathan1.0
[3] Portugal Centre1.0
[3] Saudi Arabia Guraiat and Hail1.0
[3] Morocco Casablanca0.9
[3] Senegal Dakar0.9
[3] Uganda Kampala0.9
[3] Cape Verde Southeastern Islands0.8
[3] Guinea Bissau0.8
[3] United Arab Emerates0.8
[3] Morocco Nador Metalsa Class I0.7
[3] Pakistan Karachi Parsi0.6
[3] Spain Majorca0.6
[3] China Yunnan Han pop20.5
[3] England Newcastle0.5
[3] Israel Arab Druse0.5
[3] Israel Jews0.5
[3] Italy Rome0.5
[3] Guadalajara Mestizos (2) (Mexico)0.5
[3] Morocco0.5
[3] Pakistan Sindhi0.5
[3] Senegal Niokholo Mandenka0.5
[3] Singapore Riau Malay0.5

References

1. ^{{cite journal |vauthors=Marsh SG, Albert ED, Bodmer WF, etal | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | pmc = 2396006 | doi = 10.1111/j.1399-0039.2005.00379.x }}
2. ^derived from IMGT/HLA
3. ^10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 {{cite journal |vauthors=Middleton D, Menchaca L, Rood H, Komerofsky R | title = New allele frequency database: http://www.allelefrequencies.net | journal = Tissue Antigens | volume = 61 | issue = 5 | pages = 403–7 | year = 2003 | pmid = 12753660 | doi =10.1034/j.1399-0039.2003.00062.x }}
{{HLA-B serotypes}}{{DEFAULTSORT:Hla-B42}}

1 : HLA-B alleles

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