词条 | CNQX |
释义 |
| verifiedrevid = 443492699 | ImageFile=CNQX.svg | ImageSize=240px | IUPACName=7-nitro-2,3-dioxo-1,4- dihydroquinoxaline-6-carbonitrile | OtherNames= |Section1={{Chembox Identifiers | IUPHAR_ligand = 5475 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 2951930 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = C13668 | InChI = 1/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15) | InChIKey = RPXVIAFEQBNEAX-UHFFFAOYAV | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 222418 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15) | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = RPXVIAFEQBNEAX-UHFFFAOYSA-N | CASNo_Ref = {{cascite|correct|??}} | CASNo=115066-14-3 | PubChem=3721046 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 6OTE87SCCW | SMILES = [O-][N+](=O)c1c(C#N)cc2c(c1)NC(=O)C(=O)N2 }} |Section2={{Chembox Properties | Formula=C9H4N4O4 | MolarMass=232.15 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }}CNQX or cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione) is a competitive AMPA/kainate receptor antagonist. Its chemical formula is C9H4N4O4. CNQX is often used in the retina to block the responses of OFF-bipolar cells for electrophysiology recordings.[1] See also
References1. ^{{Cite journal|title = l-Glutamate-induced responses in OFF-type bipolar cells of the cat retina|url = http://www.sciencedirect.com/science/article/pii/004269899500176X|journal = Vision Research|date = 1996-03-01|pages = 787–795|volume = 36|issue = 6|doi = 10.1016/0042-6989(95)00176-X|first = Tsugihisa|last = Sasaki|first2 = Akimichi|last2 = Kaneko}} External links
7 : AMPA receptor antagonists|Kainate receptor antagonists|Nitriles|Nitro compounds|NMDA receptor antagonists|Quinoxalines|Lactams |
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