“Humouse”的意思、由来-开放百科全书

词条

Humouse

释义

See also
References

{{Refimprove|date=March 2011}}A humouse is an immunodeficient mouse reconstituted with a human immune system, also generally known as humanised mouse. Although conventional mouse models have allowed for an increased understanding of mammalian immune systems, this knowledge cannot necessarily be directly applied to humans due to biological differences between the two species.^[1]

Humice could theoretically be used as novel pre-clinical models of the human immune system, with uses including assessing vaccine efficacy.^[2]

References

1. ^{{Cite journal|last=Hughes|first=Christopher C. W.|last2=Mestas|first2=Javier|date=2004-03-01|title=Of Mice and Not Men: Differences between Mouse and Human Immunology|url=http://www.jimmunol.org/content/172/5/2731|journal=The Journal of Immunology|language=en|volume=172|issue=5|pages=2731–2738|doi=10.4049/jimmunol.172.5.2731|issn=1550-6606|pmid=14978070}}
2. ^{{cite web|title=Baylor Institute for Immunology Research (BIIR): Humouse |url=http://www.baylorhealth.edu/Research/BIIR/humouse.htm |deadurl=yes |archiveurl=https://web.archive.org/web/20101215180808/https://baylorhealth.edu/Research/BIIR/humouse.htm |archivedate=2010-12-15 |df= }}

1 : Immunology mice

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。

See also

References