| 词条 | Hydramethylnon |
| 释义 |
| Watchedfields = changed | verifiedrevid = 461771725 | Name = Hydramethylnon | ImageFile = Hydramethylnon.png | IUPACName = 2(1H)-pyrimidinone, tetrahydro-5,5-dimethyl-, (3-(4-(trifluoromethyl)phenyl) -1-(2-(4-(trifluoromethyl)phenyl)ethenyl)-2-propenylidene)hydrazone|Section1={{Chembox Identifiers | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 4445168 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 464812 | PubChem = 5281875 | InChIKey = IQVNEKKDSLOHHK-FNCQTZNRBM | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C25H24F6N4/c1-23(2)15-32-22(33-16-23)35-34-21(13-7-17-3-9-19(10-4-17)24(26,27)28)14-8-18-5-11-20(12-6-18)25(29,30)31/h3-14H,15-16H2,1-2H3,(H2,32,33,35)/b13-7+,14-8+ | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = IQVNEKKDSLOHHK-FNCQTZNRSA-N | CASNo_Ref = {{cascite|correct|CAS}} | CASNo = 67485-29-4 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = C10994 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 38531 | SMILES = FC(F)(F)c1ccc(cc1)C=CC(=NNC2=NCC(C)(C)CN2)C=Cc3ccc(cc3)C(F)(F)F | InChI = 1/C25H24F6N4/c1-23(2)15-32-22(33-16-23)35-34-21(13-7-17-3-9-19(10-4-17)24(26,27)28)14-8-18-5-11-20(12-6-18)25(29,30)31/h3-14H,15-16H2,1-2H3,(H2,32,33,35)/b13-7+,14-8+ }} |Section2={{Chembox Properties | C=25 | H=24 | F=6 | N=4 | Appearance = Yellow to orange crystalline solid | Density = | MeltingPtC = 185 to 190 | MeltingPt_notes = | BoilingPt = |Section7={{Chembox Hazards | NFPA-H = 1 | NFPA-F = 1 | NFPA-R = 0 }}Hydramethylnon is an organic chemical compound. It is also known as AC 217,300. It is in a chemical class called trifluoromethyl aminohydrazone, which is a metabolic inhibitor. It is classified as a pesticide designed to control insects that are harmful to humans.[1] It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of oxidative phosphorylation. It is used primarily as an insecticide in the form of baits for cockroaches and ants.[2] Some brands of insecticides that include hydramethylnon are Amdro, Combat, Blatex, Cyaforce, Cyclon, Faslane, Grant's, Impact, Matox, Maxforce, Pyramdron, Siege, Scuttle and Wipeout. Hydramethylnon is a slow-acting poison with delayed toxicity that needs to be eaten to be effective.[3] ToxicologyHydramethylnon has low toxicity to mammals.[2][3] The oral {{LD50}} is 1100–1300 mg/kg in rats and above 28000 mg/kg in dogs.[3] Hydramethylnon is toxic to fish; the 96-hour LC50 in rainbow trout is 0.16 mg/L, 0.10 mg/L in channel catfish, and 1.70 mg/L in bluegill sunfish. Hydramethylnon, when fed to rats for two years led to an increase in uterine and adrenal tumors at the highest dose; therefore, the Environmental Protection Agency classifies hydramethylnon as a possible human carcinogen.[3] See also
References1. ^{{cite web | url = https://pubchem.ncbi.nlm.nih.gov/compound/hydramethylnon#section=Pharmacology-and-Biochemistry | title = Hydramethylnon | publisher = PubChem}} 2. ^1 Veterinary Support Personnel Network 3. ^1 2 3 {{cite web | url = http://npic.orst.edu/factsheets/hydragen.pdf | title = Hydramethylnon | publisher = National Pesticide Information Center}} External links
5 : Trifluoromethyl compounds|Benzene derivatives|Insecticides|Hydrazones|Alkene derivatives |
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