“Hydrodynamic radius”的意思、由来-开放百科全书

The hydrodynamic radius of a macromolecule or colloid particle is

. The macromolecule or colloid particle is a collection of

subparticles. This is done most commonly for polymers; the subparticles would then be the units of the polymer.

is defined by

where

is the distance between subparticles

and

, and where the angular brackets

represent an ensemble average.^[1] The theoretical hydrodynamic radius

was originally an estimate by John Gamble Kirkwood of the Stokes radius of a polymer, and some sources still use hydrodynamic radius as a synonym for the Stokes radius.

Note that in biophysics, hydrodynamic radius refers to the Stokes radius,^[2] or commonly to the apparent Stokes radius obtained from size exclusion chromatography.^[3]

The theoretical hydrodynamic radius

arises in the study of the dynamic properties of polymers moving in a solvent. It is often similar in magnitude to the radius of gyration.^[4]

Notes

1. ^{{cite book | author = J. Des Cloizeaux and G. Jannink | title= Polymers in Solution Their Modelling and Structure | publisher=Clarendon Press | year=1990 | isbn = 0-19-852036-0 }} Chapter 10, Section 7.4, pages 415-417.
2. ^{{cite book |last=Harding |first=Stephen |title=Protein: A comprehensive treatise |publisher=JAI Press Inc |date=1999 |pages=271–305 |chapter=Chapter 7: Protein Hydrodynamics |chapter-url=http://www.nottingham.ac.uk/ncmh/harding_pdfs/Paper216.pdf |isbn=1-55938-672-X}}
3. ^{{cite journal |last=Goto |first=Yuji |last2=Calciano |first2=Linda |last3=Fink |first3=Anthony |date=1990 |title=Acid-induced unfolding of proteins |journal=Proc. Natl. Acad. Sci. USA |volume=87 |pages=573–577|doi= 10.1073/pnas.87.2.573|pmc=53307 }}
4. ^{{cite book | author = Gert R. Strobl | title= The Physics of Polymers Concepts for Understanding Their Structures and Behavior| publisher=Springer-Verlag | year=1996 | isbn = 3-540-60768-4 }} Section 6.4 page 290.

References

Grosberg AY and Khokhlov AR. (1994) Statistical Physics of Macromolecules (translated by Atanov YA), AIP Press. {{ISBN|1-56396-071-0}}