“Hydroxynitrilase”的意思、由来-开放百科全书

词条

Hydroxynitrilase

释义

References

{{enzyme
| Name = acetone-cyanhydrin lyase
| EC_number = 4.1.2.37
| CAS_number = 112567-89-2
| IUBMB_EC_number = 4/1/2/37
| GO_code = 0047606
| image =
| width =
| caption =
}}

In enzymology, a hydroxynitrilase ({{EC number|4.1.2.37}}) is an enzyme that catalyzes the chemical reaction

acetone cyanohydrin cyanide + acetone

Hence, this enzyme has one substrate, acetone cyanohydrin, and two products, cyanide and acetone.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is acetone-cyanohydrin acetone-lyase (cyanide-forming). Other names in common use include alpha-hydroxynitrile lyase, hydroxynitrile lyase, acetone-cyanhydrin lyase [mis-spelt], acetone-cyanohydrin acetone-lyase, oxynitrilase, 2-hydroxyisobutyronitrile acetone-lyase, 2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming), and acetone-cyanohydrin lyase.

References

{{cite journal | vauthors = Xu LL, Singh BK, Conn EE |author-link3=Eric Conn | date = 1988 | title = Purification and characterization of acetone cyanohydrin lyase from Linum usitatissimum | journal = Arch. Biochem. Biophys. | volume = 263 | pages = 256–63 | pmid = 3377504 | doi = 10.1016/0003-9861(88)90634-0 | issue = 2 }}
{{cite journal | vauthors = Selmar D, Lieberei R, Biehl B, Conn EE | date = 1989 | title = alpha-Hydroxynitrile lyase in Hevea brasiliensis and its significance for rapid cyanogenesis | journal = Physiol. Plant. | volume = 75 | pages = 97–101 | doi = 10.1111/j.1399-3054.1989.tb02069.x }}

2 : EC 4.1.2|Enzymes of unknown structure

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