“Interleukin 30”的意思、由来-开放百科全书

词条

Interleukin 30

释义

References

{{Infobox_gene}}Interleukin-30 (IL-30) is a protein with a molecular weight of 28 kilodaltons, which forms one chain of the heterodimeric cytokine called interleukin 27 (IL-27), thus is sometimes called IL27-p28. The other chain of IL-27 is a molecule called Epstein-Barr induced gene-3 (EBI3). IL-30 is a member of the long-chain, 4-helix bundle family of cytokines, making it structurally similar to IL-6.^[1] This gene for this molecule is now officially called IL-27 under HGNC guidelines.^[2]

References

1. ^{{cite journal |vauthors=Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, Hibbert L, Churakova T, Travis M, Vaisberg E, Blumenschein WM, Mattson JD, Wagner JL, To W, Zurawski S, McClanahan TK, Gorman DM, Bazan JF, de Waal Malefyt R, Rennick D, Kastelein RA | title = IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells | journal = Immunity | volume = 16 | issue = 6 | pages = 779–90 |date=June 2002 | pmid = 12121660 | doi = 10.1016/S1074-7613(02)00324-2 }}
2. ^http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=19157

1 : Interleukins

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