“Intraparietal sulcus”的意思、由来-开放百科全书

The intraparietal sulcus (IPS) is located on the lateral surface of the parietal lobe, and consists of an oblique and a horizontal portion. The IPS contains a series of functionally distinct subregions that have been intensively investigated using both single cell neurophysiology in primates^[1]^[2] and human functional neuroimaging.^[3]

Its principal functions are related to perceptual-motor coordination (e.g., directing eye movements and reaching) and visual attention, which allows for visually-guided pointing, grasping, and object manipulation that can produce a desired effect.

The IPS is also thought to play a role in other functions, including processing symbolic numerical information,^[4] visuospatial working memory^[5] and interpreting the intent of others.^[6]{{ums|date=November 2017}}

Function

Five regions of the intraparietal sulcus (IPS): anterior, lateral, ventral, caudal, and medial

Activity in the intraparietal sulcus has also been associated with the learning of sequences of finger movements.^[7]

The task-positive network includes the intraparietal sulcus in each hemisphere;^[8] it is one of two sensory orienting systems in the human brain.

Understanding numbers

Behavioral studies suggest that the IPS is associated with impairments of basic numerical magnitude processing and that there is a pattern of structural and functional alternations in the IPS and in the PFC in dyscalculia.^[9] Children with developmental dyscalculia were found to have less gray matter in the left IPS.^[10]

Studies have shown that electrical activity in a particular group of nerve cells in the intraparietal sulcus spiked when, and only when, volunteers were performing calculations.

Outside experimental settings it was also found that when a patient mentioned a number—or even a quantitative reference, such as "some more", "many" or "bigger than the other one"—there was a spike of electrical activity in the same nerve-cell population of the intraparietal sulcus that was activated when the patient was doing calculations under experimental conditions.^[11]

Additional images

References

1. ^{{cite journal | doi = 10.1146/annurev.neuro.22.1.319 |author1=Colby C.E. |author2=Goldberg M.E. | year = 1999 | title = Space and attention in parietal cortex | url = | journal = Annual Review of Neuroscience | volume = 22 | issue = | pages = 319–349 | pmid = 10202542 }}
2. ^{{cite journal | doi = 10.1146/annurev.ne.12.030189.002113 | author = Andersen R.A. | year = 1989 | title = Visual and eye movement functions of the posterior parietal cortex | url = http://authors.library.caltech.edu/1195/1/ANDarn89.pdf| journal = Annual Review of Neuroscience | volume = 12 | issue = | pages = 377–403 | pmid = 2648954 }}
3. ^{{Cite journal| author1 = Culham, J.C.| author2 = Nancy G. Kanwisher| date = April 2001| title = Neuroimaging of cognitive functions in human parietal cortex| journal = Current Opinion in Neurobiology| volume = 11| issue = 2| pages = 157–163| doi = 10.1016/S0959-4388(00)00191-4| authorlink2 = Nancy G. Kanwisher }}
4. ^{{cite journal |vauthors=Cantlon J, Brannon E, Carter E, Pelphrey K | title = Functional imaging of numerical processing in adults and 4-y-old children. | journal = PLoS Biol | volume = 4 | issue = 5 | pages = e125 | year = 2006 | pmid = 16594732 | doi = 10.1371/journal.pbio.0040125 | pmc = 1431577}}
5. ^{{cite journal | doi = 10.1038/nature02466 |vauthors=Todd JJ, Marois R | year = 2004 | title = Capacity limit of visual short-term memory in human posterior parietal cortex | url = | journal = Nature | volume = 428 | issue = 6984| pages = 751–754 | pmid = 15085133 }}
6. ^{{cite journal | author = Grafton, Hamilton | title = Dartmouth Study Finds How The Brain Interprets The Intent Of Others. | journal = Science Daily | year = 2006 |url=https://www.sciencedaily.com/releases/2006/02/060216191651.htm}}
7. ^{{Cite journal | last1 = Sakai | first1 = K. | last2 = Ramnani | first2 = N. | last3 = Passingham | first3 = R. E. | title = Learning of sequences of finger movements and timing: Frontal lobe and action-oriented representation | journal = Journal of Neurophysiology | volume = 88 | issue = 4 | pages = 2035–2046 | year = 2002 | pmid = 12364526| doi = 10.1152/jn.2002.88.4.2035 }}
8. ^{{cite journal | last1 = Fox | first1 = M.D. | last2 = Corbetta | first2 = M. | last3 = Snyder | first3 = A.Z. | last4 = Vincent | first4 = J.L. | last5 = Raichle | first5 = M.E. | year = 2006 | title = Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems | url = | journal = Proceedings of the National Academy of Sciences | volume = 103 | issue = 26| pages = 10046–10051 | doi=10.1073/pnas.0604187103| pmid = 16788060 | pmc = 1480402 }}
9. ^{{cite journal | doi = 10.1016/S1364-6613(02)02040-5 |author1=Ansari D. |author2=Karmiloff-Smith A. | year = 2002 | title = Atypical trajectories of number development: a neuroconstructivist perspective | url = | journal = Trends in Cognitive Sciences | volume = 6 | issue = 12| pages = 511–516 | pmid=12475711}}
10. ^{{cite journal |vauthors=Kucian K, etal | year = 2006 | title = Impaired neural networks for approximate calculation in dyscalculic children: a functional MRI study | url = | journal = Behavior and Brain Function | volume = 2 | issue = | page = 31 | pmid = 16953876 | pmc = 1574332 | doi = 10.1186/1744-9081-2-31 }}
11. ^{{Cite journal | last1 = Dastjerdi | first1 = M. | last2 = Ozker | first2 = M. | last3 = Foster | first3 = B. L. | last4 = Rangarajan | first4 = V. | last5 = Parvizi | first5 = J. | title = Numerical processing in the human parietal cortex during experimental and natural conditions | doi = 10.1038/ncomms3528 | journal = Nature Communications | volume = 4 | pages = 2528 | year = 2013 | pmid = 24129341| pmc = 3826627}}

Function

Understanding numbers

Additional images

References

External links