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词条 Isonicotinic acid
释义

  1. Derivatives

  2. See also

  3. References

  4. External links

{{chembox
| Watchedfields = changed
| verifiedrevid = 443884866
| Reference =[1]
| Name = Isonicotinic acid
| ImageFileL1 = Isonicotinic acid.png
| ImageNameL1 = Skeletal formula
| ImageFileR1 = Isonicotinic-acid-3D-balls.png
| ImageNameR1 = Ball-and-stick model
| PIN = Pyridine-4-carboxylic acid
| OtherNames = Isonicotinic acid
4-Pyridinecarboxylic acid
p-Pyridinecarboxylic acid
4-Picolinic acid
|Section1={{Chembox Identifiers
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 6032
| SMILES = c1cnccc1C(=O)O
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 5709
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = Y8SYN761TQ
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = C07446
| InChI = 1/C6H5NO2/c8-6(9)5-1-3-7-4-2-5/h1-4H,(H,8,9)
| InChIKey = TWBYWOBDOCUKOW-UHFFFAOYAV
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1203
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C6H5NO2/c8-6(9)5-1-3-7-4-2-5/h1-4H,(H,8,9)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = TWBYWOBDOCUKOW-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 55-22-1
| PubChem = 5922
|Section2={{Chembox Properties
| C=6|H=5|N=1|O=2
| Appearance = White to off-white crystalline solid
| Density = Solid
| Solubility =
| MeltingPtC = 310
| MeltingPt_notes = (sublimes)
| pKa =
| pKb =
|Section3={{Chembox Structure
| CrystalStruct =
| Dipole =
|Section7={{Chembox Hazards
| ExternalSDS =
| MainHazards =
|Section8={{Chembox Related
| OtherCompounds = nicotinic acid, pyridine
}}

Isonicotinic acid or 4-pyridinecarboxylic acid is an organic compound with the formula C5H4N(CO2H). It is a derivative of pyridine with a carboxylic acid substituent at the 4-position. It is an isomer of picolinic acid and nicotinic acid which has the carboxyl group at the 2- and 3-position respectively compared to the 4-position for isonicotinic acid.

Derivatives

Hydrazide derivatives of isonicotinic acid include isoniazid, iproniazid, and nialamide. Amide and ester derivatives include ethionamide and dexamethasone isonicotinate.

See also

  • Pyridinecarboxylic acids

References

1. ^Isonicotinic acid at chemicalland21.com

External links

  • {{MeshName|Isonicotinic+Acids}}

2 : Aromatic acids|Pyridines

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