词条 | John W. Semple |
释义 |
The importance of understanding the T cell defects in ITP is that novel therapies aimed at these cells may significantly benefit patients with ITP. References1. ^{{Cite journal | author = JW. Semple| title = Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia | journal = Blood | volume = 78 | pages = 2619–25 | year = 1991 | pmid = 1840468 | issue = 10 |display-authors=etal}} 2. ^{{Cite journal | author = N Cooper| title = The pathogenesis of immune thrombocytopaenic purpura | journal = British Journal of Haematology | volume = 133 | pages = 364–374 | year = 2006 | pmid = 16643442 | issue = 4 | doi = 10.1111/j.1365-2141.2006.06024.x |display-authors=etal}} 3. ^{{Cite journal | author = JW Semple| title = Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity | journal = Blood | volume = 87 | pages = 4245–4254 | year = 1996 | pmid = 8639783 | issue = 10 |display-authors=etal}} 4. ^{{Cite journal | author = M Kuwana| title = Autoreactive T cells to platelet GPIIb-IIIa in immune thrombocytopenic purpura. Role in production of anti-platelet autoantibody | journal = J Clin Invest | volume = 102 | pages = 1393–1402 | year = 1998 | pmid = 9769332 | issue = 7 | doi = 10.1172/JCI4238 | pmc = 508987 |display-authors=etal}} 5. ^{{Cite journal | author = B Olsson| title = T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura | journal = Nature Medicine | volume = 9 | pages = 1123–1124 | year = 2003 | pmid = 12937414 | issue = 9 | doi = 10.1038/nm921 |display-authors=etal}} 6. ^{{Cite journal |vauthors=Stasi R, etal | title = Analysis of regulatory T cell changes in patients with idiopathic thrombocytopenic purpura receiving B-cell depleting therapy with rituximab | journal = Blood | volume = 112 | pages = 1147–1150 | year = 2008 | pmid = 18375792 | issue = 4 | doi = 10.1182/blood-2007-12-129262 }} External links
10 : Canadian medical researchers|Canadian immunologists|University of Toronto faculty|Medical educators|Living people|1959 births|Queen's University alumni|Scientists from Toronto|20th-century Canadian scientists|21st-century Canadian scientists |
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