COSMAC may refer to:

• The RCA (CDP)1802 microprocessor, aka RCA COSMAC
• The COSMAC ELF an RCA COSMAC microprocessor–based computer released 1976, sold as a kit
• The COSMAC VIP an RCA COSMAC microprocessor–based computer aimed at video games, released 1977, sold as a kit

• Huancayo (Martian crater)
• Huanchaco, Peru
• Huanchengdong Road station
• Huancuni
• Huandao Road
• Huandi Zhong
• Huan-di Zhong
• Huandong First Avenue Station
• Huan Duke of Qi
• Huaneng Coal Corporation
• Huaneng Renewables
• Huaneng Renewables Co., Ltd.
• Huaneng Renewables Company Limited
• Huaneng Renewables Corporation Limited
• Hua Ngai
• Huang Ai-chun
• Huang Ai-Chun
• Huang An (banker)
• Huang An (character)
• Huang, Andrew
• Huang An (singer)
• Huang arc
• Huang arcs
• Huangascar-Topara-Yauyos Quechua
• Huang Bairui