| 词条 | K10 transport/localisation element (TLS) |
| 释义 |
| Name = K10 transport/localisation element (TLS) | image = RF00207.jpg | width = | caption = Predicted secondary structure and sequence conservation of K10_TLS | Symbol = K10_TLS | AltSymbols = | Rfam = RF00207 | miRBase = | miRBase_family = | RNA_type = Cis-reg | Tax_domain = Eukaryota | GO = | SO = {{SO|0005836}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} The K10 transport/localisation element (TLS) is a 44 nucleotide K10 TLS regulatory element from Drosophila melanogaster. K10 TLS is responsible for the transport and anterior localisation of K10 mRNA and acts to establish dorsoventral polarity in the oocyte.[1][2] It was discovered by Julia Serano. References1. ^{{cite journal | last = Serano | first = TL |author2=Cohen RS | year = 1995 | title = A small predicted stem-loop structure mediates oocyte localization of Drosophila K10 mRNA | journal = Development | volume = 121 | pages = 3809–3818 | pmid = 8582290 | issue = 11}} 2. ^{{cite journal | last = Guillemin | first = K |author2=Williams T |author3=Krasnow MA | year = 2001 | title = A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila | journal = Nat Cell Biol | volume = 3 | pages = 848–851 | pmid = 11533666 | doi = 10.1038/ncb0901-848 | issue = 9}} External links
1 : Cis-regulatory RNA elements |
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