KGEN may refer to:

• KGEN (AM), a radio station (1370 AM) licensed to Tulare, California, United States
• KGEN-FM, a radio station (94.5 FM) licensed to Hanford, California, United States

• Owusu Ampomah
• Owusu Benson
• OWW
• O. W. Wilson
• O.W. Wilson
• O. W. Wolters
• O.W. Wolters
• Owww!
• Owyacumish River Provincial Park
• Owyhee Airport
• Owyhee County (Idaho)
• Owyhee Reservoir State Airport
• Owzthat
• OX
• OX40
• OX40 ligand
• OX4 The Best of Ride
• OX-5
• Oxabolone cipionate
• Oxaceprol
• Oxacillin
• Oxacillin sodium
• Oxadiazoles
• Oxaeid Bee
• Oxaeid bee