Lefki may refer to several places in Greece:

• Lefki, Ithaca, a village on the island of Ithaca
• Lefki, Karditsa, a village in the Karditsa regional unit, part of the municipal unit Fyllo
• Lefki, Kastoria, a village in the Kastoria regional unit, part of the municipal unit Agia Triada
• Lefki, Larissa, a village of the Elassona municipality
• Lefki, Lasithi, a municipality in Lasithi, Crete
• an alternative name of Koufonisi, Crete, an archipelago south of Crete

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