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词条 Licodione synthase
释义

  1. References

{{enzyme
| Name = Licodione synthase
| EC_number = 1.14.13.87
| CAS_number = 157972-05-9
| IUBMB_EC_number = 1/14/13/87
| GO_code =
| image =
| width =
| caption =
}}

In enzymology, a licodione synthase ({{EC number|1.14.13.87}}) is an enzyme that catalyzes the chemical reaction

liquiritigenin + NADPH + H+ + O2 licodione + NADP+ + H2O

The 4 substrates of this enzyme are liquiritigenin, NADPH, H+, and O2, whereas its 3 products are licodione, NADP+, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is liquiritigenin,NADPH:oxygen oxidoreductase (licodione-forming).

References

  • {{cite journal | vauthors = Otani K, Takahashi T, Furuya T, Ayabe S | date = 1994 | title = Licodione Synthase, a Cytochrome P450 Monooxygenase Catalyzing 2-Hydroxylation of 5-Deoxyflavanone, in Cultured Glycyrrhiza echinata L. Cells | journal = Plant Physiol. | volume = 105 | pages = 1427–1432 | pmid = 12232298 | issue = 4 | pmc = 159476 | doi = 10.1104/pp.105.4.1427 }}
  • {{cite journal | vauthors = Akashi T, Aoki T, Ayabe S | date = 1998 | title = Identification of a cytochrome P450 cDNA encoding (2S)-flavanone 2-hydroxylase of licorice (Glycyrrhiza echinata L.; Fabaceae) which represents licodione synthase and flavone synthase II | journal = FEBS Lett. | volume = 431 | pages = 287–90 | pmid = 9708921 | doi = 10.1016/S0014-5793(98)00781-9 | issue = 2 }}
{{Dioxygenases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{1.14.13-enzyme-stub}}

3 : EC 1.14.13|NADPH-dependent enzymes|Enzymes of unknown structure

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