| Celebrity | Season | Episode | Notes | | Demi Lovato | 9 | 6 | Punk'd by host Nick Cannon with the help of All Time Low. |
| Rihanna | 7 | 8 | Punk'd by host Ashton Kutcher. |
| Lauren Conrad | 9 | 7 | Punk'd by host Dax Shepard. |
| Metta World Peace | 9 | 7 | Punk'd by host Dax Shepard. |
| Chloë Grace Moretz | 9 | 7 | Punk'd by host Dax Shepard. |
| Ian Harding | 9 | 5 | Punk'd by Lucy Hale. |
| Vanessa Hudgens | 9 | 5 | Punk'd by host Lucy Hale with the help of Sarah Hyland. |
| Josh Hutcherson | 9 | 5 | Punk'd by host Lucy Hale. |
| Snooki | 9 | 3 | Punk'd by host Hayden Panettiere |
| Dianna Agron | 9 | 3 | Punk'd by host Hayden Panettiere with the help of Jessica Szohr. |
| Miley Cyrus | 9 | 1 | Punk'd by Justin Bieber. |
| Taylor Swift | 9 | 1 | Punk'd by Justin Bieber. |
| Sean Kingston | 9 | 1 | Punk'd by Justin Bieber with the help of Rob Dyrdek. |
| Raven-Symoné | 5 | 1 |
| Jessica Alba | 1 | 3 |
| Ashley Parker Angel | 7 | 1 | Hall of Shame Standard Version inductee |
| Dia Zerva | 4 | 8 |
| Ashanti | 2 | 4 | Punk'd by Ashton Kutcher along with other people at Los Angeles International Airport. |
| Jason Bateman | 5 | 5 |
| Kristen Bell | 6 | 4 |
| Halle Berry | 2 | 5 | Hall of Shame Standard Version inductee |
| Jerome Bettis | 1 | 8 | Bettis was punk'd along with Jeff Garcia and Rod Smith. |
| Beyoncé | 2 | 8 | Hall of Shame Standard Version inductee, #4 in Ashton's Top Ten Punk'ds |
| Jessica Biel | 1 | 6 |
| David Boreanaz | 6 | 3 |
| Lara Flynn Boyle | 2 | 4 |
| Hilary Swank | 8 | 2 |
| Laura Prepon | 5 | 7 |
| Bow Wow | 2 | 2 | Reappeared on Season 2 Episode 4 to set up his friend Omarion. |
| Zach Braff | 4 | 3 | Hall of Shame Standard and Overdrive Versions inductee, #2 in Ashton's Top Ten Punk'ds |
| Brandy | 3 | 6 |
| Adam Brody | 3 | 1 | Hall of Shame Overdrive Version inductee |
| Adrien Brody | 5 | 6 | Hall of Shame Standard Version inductee |
| Chamillionaire | 8 | 2 |
| Chris Brown | 7 | 4 |
| Sophia Bush | 6 | 2 |
| John Cena | 6 | 3 |
| Ryan Cabrera | 5 | 7 | Hall of Shame Standard Version inductee |
| Neve Campbell | 3 | 2 | Hall of Shame Standard Version inductee |
| Tisha Campbell-Martin | 3 | 2 | Punk'd simultaneously with Vivica A. Fox |
| Trishelle Cannatella | 1 | 5 |
| Vanessa Carlton | 4 | 7 |
| Nick Carter | 2 | 2 | He was punk'd the same way Tommy Lee was punk'd.Tommy Lee was punk'd afterwards. |
| John Cena | 8 | 8 |
| Chingy | 4 | 6 |
| Ciara | 4 | 7 | Hall of Shame Standard Version inductee |
| Rachael Leigh Cook | 2 | 5 |
| Simon Cowell | 5 | 1 | Sunday Stew's Royally Stewed Winner |
| Kaley Cuoco | 3 | 3 |
| Rosario Dawson | 1 | 8 |
| Taye Diggs | 2 | 5 |
| Eric Dill | 7 | 8 |
| Stephen Dorff | 1 | 7 |
| Hilary Duff | 2 | 1 |
| Kirsten Dunst | 4 | 2 | Hall of Shame Standard Version inductee |
| Andy Roddick | 1 | 2 |
| Zac Efron | 8 | 3 | Punk'd by Ashley Tisdale and again in season 9 by host Hayden Panettiere. |
| Carmen Electra | 3 | 5 | Punk'd together with her then-husband Dave Navarro, Hall of Shame Standard Version inductee |
| Shannon Elizabeth | 3 | 7 | Hall of Shame Standard Version Inductee |
| Missy Elliott | 2 | 1 |
| Eve | 3 | 1 | Hall of Shame Standard and Overdrive Version Inductee |
| Vivica A. Fox | 3 | 2 | Punk'd simultaneously with Tisha Campbell-Martin |
| Nelly Furtado | 8 | 1 |
| The Game | 5 | 1 | Hall of Shame Standard Version inductee |
| Jeff Garcia | 1 | 8 | Garcia was Punk'd along with Jerome Bettis and Rod Smith. |
| Jason Goldberg | 1 | 8 | Punk'd by Britney Spears, who teamed up with Kutcher. |
| Meagan Good | 8 | 5 |
| Seth Green | 1 | 5 |
| Tony Hawk | 5 | 3 |
| Salma Hayek | 4 | 1 | Hall of Shame Standard and Overdrive Versions inductee |
| Jon Heder | 4 | 6 | Hall of Shame Standard Version inductee |
| Jennifer Love Hewitt | 3 | 4 | Hall of Shame Standard Version Inductee |
| Katie Holmes | 2 | 3 | Hall of Shame Standard Version Inductee, #9 in Ashton's Top Ten Punk'ds |
| Marques Houston | 4 | 5 |
| Allen Iverson | 5 | 2 | Punk'd during his birthday party; Pulled the same prank again on his friend Jermaine O'Neal |
| Frankie J | 8 | 5 | Was tricked into thinking that he was going to meet Michael Jackson, and making him ill. |
| Jadakiss | 4 | 4 | Hall of Shame Standard Version inductee |
| Ja Rule | 5 | 7 |
| Jewel | 8 | 5 |
| JoJo | 8 | 6 |
| Magic Johnson | 8 | 4 |
| Stacy Keibler | 7 | 3 |
| Kelis | 8 | 7 |
| Chris Klein | 3 | 2 | Hall of Shame Overdrive Version Inductee |
| Mila Kunis | 5 | 6 | Sunday Stew's Royally Stewed Winner |
| Nick Lachey | 1 | 6 |
| Bucky Lasek | 8 | 1 |
| Avril Lavigne | 5 | 8 | Sunday Stew's Royally Stewed Winner |
| Tommy Lee | 2 | 2 | Nick Carter helped punk him. |
| Lisa Leslie | 5 | 6 |
| Chuck Liddell | 8 | 3 |
| Evangeline Lilly | 8 | 3 | Punk'd by former Lost co-star Harold Perrineau |
| Lindsay Lohan | 2 | 8 |
| Eva Longoria | 4 | 1 | Hall of Shame Standard and Overdrive inductee |
| George Lopez | 5 | 2 | Sunday Stew's Royally Stewed Winner |
| Benji Madden | 3 | 8 | Punk'd along with his twin brother Joel Madden of Good Charlotte |
| Joel Madden | 3 | 8 | Punk'd along with his twin brother Benji Madden of Good Charlotte; reappeared on Season 7, Episode 6 to prank Michelle Trachtenberg. |
| Jena Malone | 3 | 7 |
| Bam Margera | 3 | 7 |
| Mario | 4 | 1 |
| Danny Masterson | 6 | 5 |
| Jesse McCartney | 5 | 3 | Appeared again on Season 5, Episode 6 by playing the role of Ashton Kutcher; Sunday Stew's Royally Stewed Winner |
| Benjamin McKenzie | 5 | 5 | Set up his O.C. co-star Adam Brody back in season 3 premiere, Hall of Shame Standard Version inductee for his second appearance |
| Jesse Metcalfe | 4 | 2 | Hall of Shame Standard and Overdrive Version inductee, was the accomplice of Eva Longoria on the Season 4 premiere |
| Alyson Michalka | 8 | 8 | Punk'd by her sister Amanda Michalka. |
| Dave Mirra | 2 | 7 |
| Kelly Monaco | 6 | 2 | Hall of Shame Standard Version inductee |
| Mandy Moore | 1 | 2 | Hall of Shame Standard Version inductee |
| Tracy Morgan | 2 | 3 | Hall of Shame Standard Version Inductee, all-time record for been punk'd by the most people (six people: all from his show) |
| Frankie Muniz | 1 | 1 |
| Mýa | 2 | 3 |
| Dave Navarro | 3 | 5 | Punk'd together with his third wife Carmen Electra, Hall of Shame Standard Version inductee |
| Dirk Nowitzki | 4 | 4 |
| Jermaine O'Neal | 5 | 2 | Hall of Shame Standard Version Inductee |
| Shaquille O'Neal | 5 | 8 |
| Omarion | 2 | 4 | Appeared again on Season 4, Episode 5 to trick his friend Marques Houston |
| Jack Osbourne | 1 | 7 | Punk'd simultaneously with Wee-Man |
| Kelly Osbourne | 1 | 4 | Punk'd by Justin Timberlake, who substituted for Kutcher; Hall of Shame Standard Version inductee |
| Outkast | 2 | 7 | Punk'd simultaneously by Ashton Kutcher, Hall of Shame standard and Overdrive Version inductee |
| Hayden Panettiere | 8 | 1 |
| Kevin Richardson | 1 | 5 |
| Justin Timberlake | 1 | 1 | Hall of Shame Standard Version inductee, #1 in Ashton's Top Ten Punk'ds, punk'd Kelly Osbourne in season 1, episode 4. |
| Ashley Tisdale | 8 | 2 | Appeared again to prank Zac Efron. Was punk'd again in season 9 (episode 6) by host Nick Cannon. |
| New Boyz | 9 | 6 | Punk'd by host Nick Cannon. |
| Michelle Trachtenberg | 7 | 6 |
| Triple H | 5 | 8 | Hall of Shame Standard Version inductee |
| Tyrese | 5 | 2 |
| Usher | 2 | 1 |
| Wilmer Valderrama | 1 | 3 | Hall of Shame Standard Version Inductee |
| Sofía Vergara | 5 | 4 |
| Wee-Mann | 1 | 7 | Punk'd simultaneously with Jack Osbourne |
| Pete Wentz | 6 | 8 | Punk'd by the rest of his band (Fall Out Boy) |
| Kanye West | 3 | 8 | Hall of Shame Standard Version Inductee, #5 in Ashton's Top Ten Punk'ds |
| Serena Williams | 4 | 3 | Appeared again in season 6 to punk Venus Williams and again to punk Kelly Rowland in season 8. |
| Venus Williams | 6 | 6 | Venus gets punk'd by her sister Serena in season 6. |
| Elijah Wood | 7 | 5 | Hall of Shame Standard Edition inductee |
| Evan Rachel Wood | 3 | 4 |
| Ying Yang Twins | 6 | 1 | Punk'd simultaneously |
| Oscar De La Hoya | 6 | 2 |
| Shaun White | 6 | 6 |
| Mike Shinoda | 3 | 6 |
| Matthew Perry | 3 | 1 |
| Hugh Jackman | 7 | 8 |
| Daddy Yankee | 6 | 2 |
| Kim Kardashian | 9 | 11 | Punk'd by Ashton Kutcher |
| Drake | 9 | 11 | Punk'd by Ashton Kutcher |
| Mac Miller | 9 | 12 | Punk'd by Ashton Kutcher |
| Pink | 1 | 7 | Punk'd by boyfriend Carey Hart |