- MotoGP class 1000cc (2012–present) 800 cc (2007-2011) 990 cc (2002-2006)
- 500 cc class (1949-2002)
- 350 cc class (1949-1982)
- Moto2 class (2010–present)
- 250 cc class (1949-2009)
- Moto3 class (2012–present)
- 125 cc class (1949-2011)
- 80 cc class (1984-1989)
- 50 cc class (1962-1983)
{{MotoGP overview}}The machines participating in Grand Prix motorcycle racing, since its origin in 1949, have been entered into distinct classes depending primarily on engine capacity. The smallest engines and two-stroke engines have been phased out over the years. MotoGP class1000cc (2012–present)- Aprilia RS-GP
- Ducati Desmosedici
- Honda RC213V
- KTM RC16
- Suzuki GSX-RR
- Yamaha YZR-M1
800 cc (2007-2011)- Ducati Desmosedici
- Honda RC212V
- Ilmor X3
- Kawasaki Ninja ZX-RR
- Suzuki GSV-R
- Team Roberts KR212V
- Yamaha YZR-M1
990 cc (2002-2006)- Aprilia RS Cube
- Ducati Desmosedici
- Harris WCM
- Honda RC211V
- Kawasaki Ninja ZX-RR
- Moriwaki MD211VF
- Proton KR5
- Proton KTM
- Suzuki GSV-R
- Team Roberts KR211V
- Yamaha YZR-M1
500 cc class (1949-2002)- Aermacchi Ala d'Oro 402
- AJS Porcupine
- Aprilia RSW 500
- BMW Rennsport Typ 256
- BSA Gold Star
- BSL 500 V3
- Cagiva GP500
- ČZ 500 V4
- Ducati 500 GP
- ELF-Honda
- ELF 500 ROC
- Gilera 500
- Gilera 500 GP
- Gilera 4
- Gilera Saturno
- Harris-Yamaha
- Honda NR500
- Honda NS500
- Honda NSR500
- Honda NSR500V
- Honda NX500
- Honda RS500
- Honda RC181
- Horex 500
- Jawa Factory Racer
- Kawasaki H1A R
- Kawasaki H1R
- Kawasaki KR500
- LinTo 500 GP
- Matchless G50
- Modenas KR3
- Morbidelli 500
- Moto Guzzi 500 Four
- Moto Guzzi V8
- Muz 500
- MV Agusta 500 Shaft Drive Four
- MV Agusta 500 Six
- MV Agusta 500 Three
- MV Agusta 500 Four
- Nougier 500
- Norton Manx
- Norton NRS588
- Paton 500 GP
- Paton V115
- Paton V70
- Paton PG500R
- Paton PG500RC
- Pulse 500
- ROC-Yamaha GP1
- Sabre V4
- Sanvenero 500 GP
- Seeley G50
- Suzuki TR500
- Suzuki TSR500
- Suzuki RG500
- Suzuki RGA500
- Suzuki RGB500
- Suzuki RG 500 gamma
- Suzuki RGV500
- TSR-Honda AC50M
- Velocette Thruxton
- Vincent Grey Flash
- Yamaha TZ500
- Yamaha YZR500
350 cc class (1949-1982)- Aermacchi Ala d'Oro 350
- AJS 7R
- Bianchi 350
- ČZ 320 DOHC
- ČZ 350
- ČZ 350 V4
- Ducati 350 Desmo GP
- Harley Davidson RR350
- Honda RC170
- Honda RC171
- Honda CR77
- Honda RC172
- Honda 2RC172
- Honda RC173
- Honda RC174
- Jawa 350 Twin
- Jawa 350 V4
- Kawasaki KR350
- MV Agusta 350 Twin
- MV Agusta 350 Three
- MV Agusta 350 Six
- MV Agusta 350 Four
- MZ 350 Twin
- Norton Kneeler
- Yamaha 350 Triple
- Yamaha TZ350
- Yamaha TR2
- Yamaha TR3
- Yamaha YZR350
Moto2 class (2010–present)- FTR Moto M210
- FTR Moto M211
- FTR Moto M212
- FTR Moto M213
- TSR TSR6
- Bimota HB4
- Suter MMX
- Suter MMX2
- Suter MMXI
- Suter MMXII
- Harris Moto2
- BQR-Moto2
- MZ Moto2
- Moriwaki MD600
- Force GP210
- RSV Motor DR600
- I.C.P. Textra
- Kalex Moto2
- Tech 3 Mistral 610
- MIR Moto2
- AJR Moto2
- AJR EVO 2012
- ADV AT02
- RBB Moto2
- Ten Kate Moto2
- IAMT Moto2
- Speed Up S12
- Speed Up SF13
- Speed Up SF14
- Motobi TSR6
- TransFIORmers
- Forward KLX
- TaylorMade Carbon 2
- NTS NH6
250 cc class (1949-2009)- Aprilia AFI
- Aprilia RSW 250
- Aprilia RSA 250
- Aprilia RSV 250
- Benelli 250 DOHC
- Bianchi 250
- Bultaco 250
- ČZ 250
- Gilera 250
- Harley-Davidson RR250
- Honda 220cc prototype (1954)
- Honda 250 6 Cyls
- Honda 250 4 Cyls
- Honda NSR250
- Honda RS250
- Honda RS250R
- Honda RC160
- Honda RC161
- Honda RC162
- Honda RC163
- Honda CR72
- Honda RC164
- Honda 3RC164
- Honda RC165
- Honda RC166
- Honda RC166
- Jawa 250 Single
- Jawa 250 Twin
- Kawasaki KR250
- KTM 250 FRR
- Motobi 250
- Moto Guzzi 250
- Moto Guzzi Albatross
- Moto Guzzi Gambalunghino
- Moto Guzzi Dondolino
- Moto Guzzi Gambalunga
- Montesa 250
- Morbidelli 250
- MV Agusta 250 Single
- MV Agusta 250 Twin
- MZ RZ 250 Twin
- New Imperial 250
- Ossa 250
- Puch 250
- Rudge 250 Sports
- Suzuki 250 RGV-XR Twin
- Villa 250
- Walter 250
- Yamaha 250 Twin
- Yamaha 250 V4
- Yamaha YZR250
- Yamaha TZ250
- Yamaha RD56
- Yamaha RD48
Moto3 class (2012–present)- Honda NSF250R
- Honda NSF250RW
- Ioda TR002
- FTR M312
- FTR M313
- KRP M3-01
- KRP M3-02
- Suter MMX3
- Oral M3
- Mahindra MGP3O
- FGR 250 GP
- MIR Racing Moto3
- TSR TSR3
- TSR3C
- FGR 250 GP
- KTM RC250GP
- KTM RC250R
- Kalex KTM
- EvL250
- Husqvarna FR250GP
125 cc class (1949-2011)- Aprilia RS 125 R
- Aprilia RSW125
- Aprilia RSA125
- Bultaco 125
- ČZ 125
- ČZ 125 Twin
- Derbi 125
- Derbi 125 V-Twin
- Gilera 125
- Gilera Mosca Bianca 125
- Honda RC142
- Honda RC143
- Honda 2RC143
- Honda RC144
- Honda RC145
- Honda CR93
- Honda 2RC146
- Honda 4RC146
- Honda RC148
- Honda RC149
- Honda RS125
- Jawa 125 Twin
- Lube 125
- KTM 125 FRR
- Maxtra 125
- Mondial 125SS
- Mondial 175 DOHC
- Morbidelli 125
- Motobécane 125
- Motobi 175
- Motobi 125
- MV Agusta 98/125 Two Stroke
- MV Agusta 125 Twin-Cam
- MV Agusta 125 SOHC
- MV Agusta 125 DOHC
- MV Agusta 125 Disc Valve
- MZ RD 125 Triple
- MZ RE 125
- MZ RZ 125 Tandem
- Parilla 175 Production Racer
- Puch 125
- Suzuki 125 V4
- Yamaha AS1
- Yamaha AS3
- Yamaha TA125
- Yamaha TZ125
- Yamaha 125 V4
80 cc class (1984-1989)- Derbi 80
- HuVo-Casal 80
- Krauser 80
- Zündapp 80
50 cc class (1962-1983){{main|50 cc}}- Bultaco TSS 50
- Derbi 50
- Ducson 50
- Gilera 4
- Honda CR110
- Honda RC110
- Honda RC111
- Honda RC112
- Honda RC113
- Honda RC114
- Honda RC115
- Honda RC116
- Itom 50
- Jamathi 50
- Kreidler 50 GP
- Kreidler 50 Van Veen
- Monark 50
- Morbidelli 50
- MZ RE 50
- Suzuki 50 Single
- Suzuki 50 Twin
- Tomos D3
- Tomos D5
- Tomos D6
- Tomos D7
- Tomos D9
- Tomos DMPG
- Tomos DMPG GP75
- Tomos DMPG GP78
- Tomos DMPG GP79
{{MotoGP}}{{DEFAULTSORT:Grand Prix motorcycles}} 2 : Motorcycle sport lists|Lists of motorcycles |