Little Jack may refer to:

• Little Jack Horner, a children's nursery rhyme
• Little Jack, a mountain in Washington state
• Little Jack Sheppard, a burlesque play
• Little Jack, an airship in the video game Skies of Arcadia

• Priocera chiricahuae
• Priocnemis minorata
• Priodas Pum Mil
• Priodontina
• Priognathus
• Priol (Goa Assembly constituency)
• Priolo, Steve
• Prionailurus bengalensis bengalensis
• Prionailurus javanensis
• Prionastraea
• Prionastraea abdita
• Prionastraea australensis
• Prionastraea crassior
• Prionastraea gibbosa
• Prionastraea gibbosissima
• Prionastraea magnifica
• Prionastraea obtusata
• Prionastraea profundicella
• Prionastraea quoyi
• Prionastraea robusta
• Prionastraea seychellensis
• Prionastraea spectabilis
• Prionastraea spinosa
• Prionastraea sulfurea
• Prionastraea tesserifera