| 词条 | L-myc internal ribosome entry site (IRES) |
| 释义 |
| Name = L-myc internal ribosome entry site (IRES) | image = RF00261.jpg | width = | caption = Predicted secondary structure and sequence conservation of IRES_L-myc | Symbol = IRES_L-myc | AltSymbols = | Rfam = RF00261 | miRBase = | miRBase_family = | RNA_type = Cis-reg; IRES | Tax_domain = Eukaryota | GO = {{GO|0043022}} | SO = {{SO|0000243}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} The L-myc internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of L-myc that allows cap-independent translation. L-myc undergoes translation via the internal ribosome entry site and bypasses the typical eukaryotic cap-dependent translation pathway [1]. The myc family of genes when expressed are known to be involved in the control of cell growth, differentiation and apoptosis. References
External links
1 : Cis-regulatory RNA elements |
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