LOTD may stand for:

• Lesson of the Day- used especially on Twitter
• Land of the Dead, the fourth movie in George A. Romero's "Dead Series"
• Linux on the Desktop, Linux on the Desktop
• Lord of the Dance (disambiguation)
• Laws of thermodynamics, physics laws that describe the specifics for the transport of heat and work in thermodynamic processes
• Legion of the Damned (band), a Dutch thrash/death metal band

• Pacific Lacefern
• Pacific (LACMTA Station)
• Pacific ladyfish
• Pacific Lamprey
• Pacific lamprey
• Pacific Life
• Pacific LifeCorp
• Pacific Life Insurance
• Pacific Life Insurance Company
• Pacific Life Open
• Pacific Light and Power Company
• Pacific Lightnet
• Pacific LightNet
• Pacific Linguistics
• Pacific Locomotive Association
• Pacific long-tailed cuckoo
• Pacific Lumber Company
• Pacific lutheran rowing
• Pacific Lutheran Theological Seminary
• Pacific Lutheran University Crew
• Pacific lutheran university rowing
• Pacific mackerel
• Pacific Madrona
• Pacific madrone
• Pacific Magazines