| 词条 | Lymphangitis carcinomatosa |
| 释义 |
| name = | synonyms = | image = | alt = | caption = | pronounce = | synonym = | field = Oncology | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} Lymphangitis carcinomatosa is inflammation of the lymph vessels (lymphangitis) caused by a malignancy. Breast, lung, stomach, pancreas, and prostate cancers are the most common tumors that result in lymphangitis. Lymphangitis carcinomatosa was first described by pathologist Gabriel Andral in 1829 in a patient with uterine cancer. Lymphangitis carcinomatosa may show the presence of Kerley B lines on chest X-ray. Lymphangitis carcinomatosa most often affects people 40–49 years of age.[1] Lymphangitis carcinomatosa may be caused by the following malignancies as suggested by the mnemonic: "Certain Cancers Spread By Plugging The Lymphatics" (cervical cancer, colon cancer, stomach cancer, breast cancer/bronchiogenic carcinoma, pancreatic cancer, thyroid cancer, laryngeal cancer) PathologyIn most cases, lymphangitis carcinomatosis is caused by the dissemination of a tumor with its cells along the lymphatics.[2] However, in about 20 percent of cases, the inflammation of the lymphatic tubules (lymphangitis) is caused by a tumor that blocks the drainage of the lymph duct. In the lung, this is often caused by a centrally located mass, near the hilum of the lung that blocks lymphatic drainage. PrognosisPreviously, the finding of lymphangitis carcinomatosis meant about a six-month life expectancy.[2] However, improved treatment has improved survival in patients with lymphangitis carcinomatosis, with patients often surviving three or more years with treatment.[2] HistoryLymphangitis carcinomatosa was first described by pathologist Gabriel Andral in 1829 in a patient with uterine cancer.[3] See also
References1. ^{{cite journal | vauthors = Bruce DM, Heys SD, Eremin O |date=February 1996 | title = Lymphangitis carcinomatosa: a literature review. | journal = J R Coll Surg Edinb. | volume = 41 | issue = 1 | pages = 7–13 | pmid = 8930034}} 2. ^1 2 {{cite book|last1=McKean|first1=Sylvia|last2=Jacobson|first2=FL|title=Principles and practice of hospital medicine: Chapter 108: Advanced Cardiothoracic Imaging|date=2012|publisher=McGraw-Hill|location=New York|isbn=9780071603898}} 3. ^{{cite journal | author = Doyle L. |date=August 1989 | title = Gabriel Andral (1797–1876) and the first reports of lymphangitis carcinomatosa | journal = J R Soc Med | volume = 82 | issue = 8 | pages = 491–3 | pmid = 2674433 | pmc = 1292257}} External links{{Medical resources| DiseasesDB = 7672 | ICD10 = | ICD9 = | ICDO = | OMIM = | MedlinePlus = | MeSH = | GeneReviewsNBK = | GeneReviewsName = | Orphanet = }} 2 : Paraneoplastic syndromes|Medical mnemonics |
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