| 词条 | Magnesium gluconate |
| 释义 |
| ImageFile = magnesium gluconate.svg | IUPACName = Magnesium bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate] | OtherNames = |Section1={{Chembox Identifiers | CASNo = 3632-91-5 | CASNo_Ref = {{cascite|correct|CAS}} | PubChem = 11418570 | ChEMBL = 2107145 | ChemSpiderID = 9593457 | SMILES = [Mg+2].[O-]C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[O-]C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO | InChI = InChI=1S/2C6H12O7.Mg/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1 |Section2={{Chembox Properties | C=12 | H=22 | Mg=1 | O=14 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = |Section6={{Chembox Pharmacology | ATCCode_prefix = A12 | ATCCode_suffix = CC03 }} |Section7={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} Magnesium gluconate is a compound with formula MgC12H22O14. It is the magnesium salt of gluconic acid. According to one study, magnesium gluconate showed the highest level of bioavailability of any magnesium salt which implies its viability as a supplement, although of the 10 salts studied, all increased Magnesium levels significantly.[1] It has E number "E580". Use in medicineThere are data on the pharmacological properties of magnesium gluconate. Gluconic acid is the initial substrate for the reactions of pentose phosphate path of oxidation of glucose, so it was suggested that it may affect the energy metabolism of mitochondria.{{Citation needed|date=April 2011}} In Ukraine, magnesium gluconate, together with potassium gluconate in the drug Rhythmocor is used to treat heart disease. Pilot studies have shown efficacy in various cardiac arrhythmia.[2] Whether these effects are from the influence of gluconic acid on the metabolism of the heart or from the influence of magnesium and potassium on osmotic pressure is unknown. References1. ^{{Cite journal | last1 = Coudray | first1 = C | last2 = Rambeau | first2 = M | last3 = Feillet-Coudray | first3 = C | last4 = Gueux | first4 = E | last5 = Tressol | first5 = JC | last6 = Mazur | first6 = A | last7 = Rayssiguier | first7 = Y | title = Study of magnesium bioavailability from ten organic and inorganic Mg salts in Mg-depleted rats using a stable isotope approach | journal = Magnesium Research | volume = 18 | issue = 4 | pages = 215–23 | year = 2005 | pmid = 16548135}} {{DEFAULTSORT:Magnesium Gluconate}}2. ^{{cite journal |title=On Synergism of Potassium and Magnesium in Maintenance of Myocardial Function| pmid=28294893}} 2 : Gluconates|Magnesium compounds |
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