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词条 Maleylpyruvate isomerase
释义

  1. Structural studies

  2. References

{{enzyme
| Name = maleylpyruvate isomerase
| EC_number = 5.2.1.4
| CAS_number = 9023-77-2
| IUBMB_EC_number = 5/2/1/4
| GO_code = 0050077
| image =
| width =
| caption =
}}

In enzymology, a maleylpyruvate isomerase ({{EC number|5.2.1.4}}) is an enzyme that catalyzes the chemical reaction

3-maleylpyruvate 3-fumarylpyruvate

Hence, this enzyme has one substrate, 3-maleylpyruvate, and one product, 3-fumarylpyruvate.

This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is 3-maleylpyruvate cis-trans-isomerase. This enzyme participates in tyrosine metabolism.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|2NSF}} and {{PDB link|2NSG}}.

References

  • {{cite journal | vauthors = Lack L | title = Enzymic cis-trans isomerization of maleylpyruvic acid | journal = The Journal of Biological Chemistry | volume = 236 | pages = 2835–40 | date = November 1961 | pmid = 14461395 }}
{{Geometric isomerases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{isomerase-stub}}

2 : EC 5.2.1|Enzymes of known structure

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