MCDC may refer to:

• Malta Coins Distribution Centre
• Minuteman Civil Defense Corps
• Mandalay City Development Committee
• Modified Condition/Decision Coverage
• Music Choice/Dance Channel
• Multiprogram Computational Data Center, a proposed expansion of the U.S. National Security Agency's Multiprogram Research Facility
• MCDC, Canlubang

• The Last Voyage of the Enterprise
• The Last Voyage of the USS Enterprise
• The Last Voyage of the U.S.S. Enterprise
• The Last Waltz (1934 film)
• The Last Waltz (1936 British film)
• The Last Waltz (1936 English film)
• The Last Waltz (1936 film)
• The Last Waltz (1936 French film)
• The Last Waltz (1953 film)
• The Last Waltz (1978 film)
• The Last Waltz (film)
• The Last Waltz King
• The Last Warning (1938 film)
• The Last Warrior (2017 film)
• The Last Wedding
• The Last Wedding (New Girl)
• The Last Whole Earth Catalog
• The Last Will and Testament of Senhor da Silva Araujo
• The Last Will and Testament of Senhor da Silva Araújo
• The Last Will Be the Last
• The Last Will of a Russian fascist
• The Last Witch
• The last witness
• The Last Witness (1921 film)
• The Last Witness (2018 film)