| 词条 | Meprodine |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 447991486 | IUPAC_name = (3S,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propionate | image = Alphameprodine.svg | width = 160 | caption = Alpha-meprodine | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = S9 | legal_CA = Schedule I | legal_UK = | legal_US = Schedule I | legal_DE = Anlage I | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 468-51-9 | ATC_prefix = none | ATC_suffix = | PubChem = 61119 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 2104027 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 16736823 | C=17 | H=25 | N=1 | O=2 | molecular_weight = 275.39 g/mol | smiles = CC[C@H]1CN(C)CC[C@@]1(OC(=O)CC)c2ccccc2 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C17H25NO2/c1-4-14-13-18(3)12-11-17(14,20-16(19)5-2)15-9-7-6-8-10-15/h6-10,14H,4-5,11-13H2,1-3H3/t14-,17-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = ODEGQXRCQDVXSJ-YOEHRIQHSA-N }} Meprodine is an opioid analgesic that is an analogue of pethidine (meperidine). It is closely related to the drug prodine, the only difference being that meprodine has an ethyl group rather than a methyl at the 3-position of the piperidine ring. As with prodine, there are two isomers of meprodine, alpha-meprodine and beta-meprodine, with the alpha isomer having been more widely used. Alphameprodine (ACSCN 9604) and betameprodine (ACSCN 9608) are both Schedule I Narcotic controlled substances in the United States, both with annual aggregate manufacturing quotas of 2 grammes as of 2014.[1] Meprodine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening. Legal StatusAustraliaMeprodine is considered a Schedule 9 prohibited substance in Australia under the Poisons Standard (February 2017).[2] A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities.[2] References1. ^http://www.deadiversion.usdoj.gov/fed_regs/quotas/2014/fr0825.htm {{Opioidergics}}{{analgesic-stub}}2. ^1 Poisons Standard October 2015 https://www.legislation.gov.au/Details/F2017L00057 4 : Synthetic opioids|Propionate esters|Piperidines|Mu-opioid agonists |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。