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词条 Methanosarcina-phenazine hydrogenase
释义

  1. References

{{enzyme
| Name = Methanosarcina-phenazine hydrogenase
| EC_number = 1.12.98.3
| CAS_number = 9027-05-8
| IUBMB_EC_number = 1/12/98/3
| GO_code = 0051911
| image =
| width =
| caption =
}}

In enzymology, a Methanosarcina-phenazine hydrogenase ({{EC number|1.12.98.3}}) is an enzyme that catalyzes the chemical reaction

H2 + 2-(2,3-dihydropentaprenyloxy)phenazine 2-dihydropentaprenyloxyphenazine

Thus, the two substrates of this enzyme are H2 and 2-(2,3-dihydropentaprenyloxy)phenazine, whereas its product is 2-dihydropentaprenyloxyphenazine.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with other, known, acceptors. The systematic name of this enzyme class is hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase. Other names in common use include methanophenazine hydrogenase, and methylviologen-reducing hydrogenase.

References

  • {{cite journal | vauthors = Abken HJ, Tietze M, Brodersen J, Baumer S, Beifuss U, Deppenmeier U | date = 1998 | title = Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Go1 | journal = J. Bacteriol. | volume = 180 | pages = 2027–32 | pmid = 9555882 | issue = 8 | pmc = 107126 }}
  • {{cite journal | vauthors = Deppenmeier U, Lienard T, Gottschalk G | date = 1999 | title = Novel reactions involved in energy conservation by methanogenic archaea | journal = FEBS Lett. | volume = 457 | pages = 291–7 | pmid = 10471795 | doi = 10.1016/S0014-5793(99)01026-1 | issue = 3 }}
  • {{cite journal | vauthors = Beifuss U, Tietze M, Baumer S, Deppenmeier U | date = 2000 | title = Methanophenazine: Structure, Total Synthesis, and Function of a New Cofactor from Methanogenic Archaea This work was supported by the Deutsche Forschungsgemeinschaft (Sonderforschungsbereich 416; grants De 488/6-1 and De 488/4-2) and the Fonds der Chemischen Industrie We are grateful to Drs. J. Paust and H. Jaedicke (BASF AG, Ludwigshafen) and Dr. R. K. Muller (Hoffmann-La Roche Ltd., Basel) for generously providing chemicals | journal = Angew. Chem. Int. Ed. Engl. | volume = 39 | pages = 2470–2472 | pmid = 10941105 | issue = 14 | doi = 10.1002/1521-3773(20000717)39:14<2470::AID-ANIE2470>3.0.CO;2-R }}
{{Hydrogen oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{1.12-enzyme-stub}}

2 : EC 1.12.98|Enzymes of unknown structure

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