| 词条 | Methyl-MMDA-2 |
| 释义 |
| IUPAC_name = N-methyl-1-(6-methoxy-1,3-benzodioxol-5-yl)propan-2-amine | image = Methyl-MMDA-2-structure.png | tradename = | pregnancy_category = | legal_status = Uncontrolled (but may be covered under the Federal Analogue Act in the United States and under similar bills in other countries) | routes_of_administration = Oral, Insufflated, Rectal | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number = 108925-34-4 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = | ATC_prefix = none | ATC_suffix = | PubChem = ? | ChemSpiderID = 23553107 | C=12 | H=17 | N=1 | O=3 | molecular_weight = 223.27 g/mol | smiles = CC(Cc1cc2c(cc1OC)OCO2)NC }}N-Methyl-2-methoxy-4,5-methylenedioxyamphetamine (methyl-MMDA-2; 6-methoxy-MDMA) is a psychedelic drug of the amphetamine class.[1] It is the N-methylated derivative of MMDA-2, and is also an analog of MDMA and 6-methyl-MDA.[1] Methyl-MMDA-2 was first synthesized by Alexander Shulgin and was described in his book PiHKAL. He states that it is essentially inactive at a dose of 70 mg, and he did not try any higher;[1] however, Methyl-MMDA-2 is still likely to be active, perhaps in the 125-250 mg range.{{Citation needed|date=April 2010}} This reduction in hallucinogenic activity relative to MMDA-2 parallels that of MDA and MDMA, indicating that with phenethylamines, N-methylation substantially reduces 5-HT2A receptor affinity.[1][2] See also
References1. ^1 2 3 {{cite book | author = Ann Shulgin | author2 = Alexander Shulgin | title = Pihkal: A Chemical Love Story | publisher = Transform Press | location = | year = 1991 | pages = | isbn = 0-9630096-0-5 | oclc = | doi = | url = http://isomerdesign.com/PiHKAL/read.php?domain=pk&id=131}} 2. ^{{cite journal | vauthors = Nichols DE, Oberlender R | title = Structure-activity relationships of MDMA-like substances | journal = NIDA Research Monograph | volume = 94 | issue = | pages = 1–29 | year = 1989 | pmid = 2575223 | doi = | url = }} External links
3 : Methamphetamines|Benzodioxoles|Serotonin receptor agonists |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。