| 词条 | Michael Neuberger |
| 释义 |
| name = Michael Neuberger | birth_name = Michael Samuel Neuberger | image = | image_size = | alt = | caption = | birth_date = {{Birth date|df=yes|1953|11|2}}[1] | birth_place = London, United Kingdom | death_date = {{Death date and age|df=yes|2013|10|26|1953|11|2}} | death_place = Cambridge, United Kingdom | residence = | citizenship = | nationality = British | fields = | workplaces = Laboratory of Molecular Biology | alma_mater = {{Plainlist|
| thesis_url = http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.466977 |thesis_title = Transducing phages for analysis of gene duplications | thesis_year = 1978 | doctoral_advisor = Brian S. Hartley | academic_advisors = | doctoral_students = | notable_students = | known_for = | influences = | influenced = | awards = {{Plainlist|
| signature = | signature_alt = | footnotes = | spouse = }}Michael Samuel Neuberger FRS FMedSci (2 November 1953 – 26 October 2013) was a British biochemist and immunologist.[2][3][4][5] EducationBorn in London, he was educated at Westminster School, and then read Natural Sciences at Trinity College, Cambridge as a scholar where he obtained a Master of Arts; he then obtained a PhD at Imperial College, London.[6][7] CareerHe was a fellow of, and director of studies at Trinity College, Cambridge from 1985[8] and Professor of molecular immunology there since 2002. He supervised students reading the Natural Sciences Tripos in the fields of cell biology and biochemistry. He was also joint head of the Protein and Nucleic Acid Chemistry division at the Medical Research Council's Laboratory of Molecular Biology in Cambridge, UK,[9] alongside Mariann Bienz.[10] He is most notable for discovering the mechanism of somatic hypermutation. Awards and honoursHe was elected a Fellow of the Royal Society (FRS) in 1993[11] and was awarded their GlaxoSmithKline Prize in 2003. He also received the Novartis medal in 2002 and delivered the Novartis medal lecture, entitled "Antibodies: a Paradigm for the Evolution of Molecular Recognition" on 9 April 2002 at Heriot-Watt University, Edinburgh. Personal lifeHe was the son of Albert Neuberger, the brother of David Neuberger, James Neuberger, and Anthony Neuberger, and the brother-in-law of Julia Neuberger. He died of myeloma, a cancer of antibody-producing cells, at Addenbrooke's Hospital, Cambridge, on 26 October 2013. References1. ^{{cite web|url=http://www.debretts.com/people/biographies/browse/n/5243/Michael%20Samuel+NEUBERGER.aspx |title=Prof Michael Neuberger, FRS Authorised Biography |publisher=Debretts.com |accessdate=2 December 2013}} {{FRS 1993}}{{Authority control}}{{DEFAULTSORT:Neuberger, Michael}}{{UK-biochemist-stub}}2. ^{{Cite journal | last1 = Cattaneo | first1 = A. | last2 = Sitia | first2 = R. | doi = 10.1038/emboj.2013.251 | title = Remembering Michael S Neuberger (1953-2013) | journal = The EMBO Journal | volume = 32 | issue = 24 | pages = 3112–3113 | year = 2013 | pmc = 3981150 }} 3. ^{{cite web|url=http://www2.mrc-lmb.cam.ac.uk/michael-neuberger-1953-2013/ |title=Michael_Neuberger Obituary|publisher= Medical Research Council|archiveurl=https://web.archive.org/web/20151208092258/http://www2.mrc-lmb.cam.ac.uk/michael-neuberger-1953-2013/|archivedate=8 December 2015}} 4. ^{{cite journal|last1=Rajewsky|first1=K.|title=Michael S. Neuberger 1953–2013|journal=Proceedings of the National Academy of Sciences|pmc=3939883|volume=111|issue=8|year=2014|pages=2862–2863|issn=0027-8424|doi=10.1073/pnas.1401334111|pmid=24532658}} 5. ^{{cite journal|last1=Gearhart|first1=Patricia J.|last2=Kelsoe|first2=Garnett|title=A tribute to Michael S. Neuberger|journal=Journal of Clinical Investigation|volume=124|issue=1|year=2014|pages=3–5|issn=0021-9738|doi=10.1172/JCI74366|pmc=3871264|pmid=24382382}} {{open access}} 6. ^{{cite thesis|degree=PhD|publisher=University of London|title=Transducing phages for analysis of gene duplications|first= Michael Samuel|last=Neuberger|year=1978|url=http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.466977|oclc=500526968}} 7. ^{{cite web|author=KJ Patel|authorlink1=Ketan J. Patel |url=https://www.theguardian.com/science/2013/dec/01/michael-neuberger |title=Michael Neuberger obituary |work=The Guardian |accessdate=2 December 2013}} 8. ^{{cite web|url=http://www.trin.cam.ac.uk/index.php?pageid=176&conid=72|title=Trinity College directory of Fellows|accessdate=22 December 2010}} 9. ^{{Cite journal | last1 = Jones | first1 = P. T. | last2 = Dear | first2 = P. H. | last3 = Foote | first3 = J. | last4 = Neuberger | first4 = M. S. | last5 = Winter | first5 = G. | title = Replacing the complementarity-determining regions in a human antibody with those from a mouse | doi = 10.1038/321522a0 | journal = Nature | volume = 321 | issue = 6069 | pages = 522–525 | year = 1986 | pmid = 3713831}} 10. ^{{cite web|url=http://www2.mrc-lmb.cam.ac.uk/research/pnac |title=Protein and Nucleic Acid Chemistry Division |publisher=MRC Laboratory of Molecular Biology |date=17 October 2013 |accessdate=2 December 2013}} 11. ^1 {{cite web |title=Fellowship of the Royal Society 1660–2015 |url=https://docs.google.com/spreadsheets/d/1RVVZY00MZNrK2YCTTzVrbTFH2t3RxoAZah128gQR-NM/pubhtml |publisher=Royal Society |location=London |archiveurl=https://www.webcitation.org/6a2i9QICV?url=https://docs.google.com/spreadsheets/d/1RVVZY00MZNrK2YCTTzVrbTFH2t3RxoAZah128gQR-NM/pubhtml |archivedate=15 July 2015 |deadurl=yes |df= }} 14 : 1953 births|2013 deaths|People educated at Westminster School, London|Alumni of Trinity College, Cambridge|Alumni of Imperial College London|Fellows of Trinity College, Cambridge|Fellows of the Royal Society|Members of the European Molecular Biology Organization|British biochemists|English Jews|Jewish scientists|Neuberger family|English people of German-Jewish descent|Deaths from multiple myeloma |
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