| 词条 | Mir-166 microRNA precursor |
| 释义 |
| Name = mir-166 microRNA precursor | image = RF00075.jpg | width = | caption = Predicted secondary structure and sequence conservation of mir-166 | Symbol = mir-166 | AltSymbols = | Rfam = RF00075 | miRBase =MI0000201 | miRBase_family = MIPF0000004 | RNA_type = Gene; miRNA | Tax_domain = Eukaryota | GO = {{GO|0035195}} {{GO|0035068}} | SO = {{SO|0001244}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} The plant mir-166 microRNA precursor is a small non-coding RNA gene. This microRNA (miRNA) has now been predicted or experimentally confirmed in a wide range of plant species.[1] microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product.[2] In this case the mature sequence comes from the 3' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences.[3] The mature products are thought to have regulatory roles through complementarity to messenger RNA. References1. ^{{cite web|title=miRNA gene family: MIR166|url=http://www.mirbase.org/cgi-bin/mirna_summary.pl?fam=MIPF0000004|work=mirBASE|publisher=University of Manchester|accessdate=5 September 2011}} 2. ^{{cite journal | last = Ambros | first = V | year = 2001 | title = microRNAs: tiny regulators with great potential | journal = Cell | volume = 107 | pages = 823–826 | pmid = 11779458 | doi = 10.1016/S0092-8674(01)00616-X | issue = 7}} 3. ^{{cite journal | last = Reinhart | first = BJ |author2=Weinstein EG |author3=Rhoades MW |author4=Bartel B |author5=Bartel DP | year = 2002 | title = MicroRNAs in plants | journal = Genes Dev | volume = 16 | pages = 1616–1626 | pmid = 12101121 | doi = 10.1101/gad.1004402 | issue = 13 | pmc = 186362}} External links
1 : MicroRNA |
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