词条 | Mir-194 microRNA precursor family |
释义 |
| Name = mir-194 microRNA precursor family | image = RF00257.jpg | width = | caption = Predicted secondary structure and sequence conservation of mir-194 | Symbol = mir-194 | AltSymbols = | Rfam = RF00257 | miRBase = MI0000488 | miRBase_family = MIPF0000055 | RNA_type = Gene; miRNA | Tax_domain = Eukaryota | GO = {{GO|0035195}} {{GO|0035068}} | SO = {{SO|0001244}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} In molecular biology, miR-194 microRNA precursor is a small non-coding RNA gene that regulated gene expression. Its expression has been verified in mouse (MI0000236, MI0000733)[1] and in human (MI0000488, MI0000732{{dead link|date=February 2018 |bot=InternetArchiveBot |fix-attempted=yes }}).[2] mir-194 appears to be a vertebrate-specific miRNA and has now been predicted or experimentally confirmed in a range of vertebrate species (MIPF0000055). The mature microRNA is processed from the longer hairpin precursor by the Dicer enzyme. In this case, the mature sequence is excised from the 5' arm of the hairpin. See also
References1. ^{{cite journal | vauthors = Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T | title = New microRNAs from mouse and human | journal = RNA | volume = 9 | issue = 2 | pages = 175–9 | date = Feb 2003 | pmid = 12554859 | pmc = 1370382 | doi = 10.1261/rna.2146903 }} 2. ^{{cite journal | vauthors = Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ | title = Reduced accumulation of specific microRNAs in colorectal neoplasia | journal = Molecular Cancer Research | volume = 1 | issue = 12 | pages = 882–91 | date = Oct 2003 | pmid = 14573789 }} External links
2 : MicroRNA|MicroRNA precursor families |
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