Mister Blues may refer to:

• Wynonie Harris (1915–1969) (aka Mister Blues), an American blues shouter and rhythm and blues singer
• "Mister Blues", a song bye Moby Grape from their 1967 album Moby Grape
• "Mister Blues", Blues Band from Germany.

• 1945–46 Netherlands Football League Championship
• 1945–46 Newport County A.F.C. season
• 1945–46 New York Rangers season
• 1945–46 Northern Rugby Football League season
• 1945–46 OHA season
• 1945–46 Oklahoma A&M Aggies men's basketball team
• 1945–46 Portuguese Liga
• 1945–46 Primeira Divisão
• 1945–46 Segunda Division
• 1945–46 Segunda División
• 1945–46 Serie B-C Alta Italia
• 1945–46 Serie C
• 1945–46 Southern Football League
• 1945–46 Southern League Cup (Scotland)
• 1945–46 Swedish football Division 2
• 1945–46 Texas Tech Red Raiders basketball team
• 1945–46 Toronto Maple Leafs season
• 1945–46 İstanbul Football League
• 1946/1947 football season in Switzerland
• 1946-1947 United States network television schedule
• 19461 Feingold
• 19462 Ulissedini
• 19463 Emilystoll
• 1946-47 AHL season
• 1946-47 Allsvenskan