“Muconolactone Delta-isomerase”的意思、由来-开放百科全书

词条

Muconolactone Delta-isomerase

释义

Structural studies
References

{{enzyme
| Name = muconolactone delta-isomerase
| EC_number = 5.3.3.4
| CAS_number = 37318-46-0
| IUBMB_EC_number = 5/3/3/4
| GO_code = 0016159
| image =
| width =
| caption =
}}

In enzymology, a muconolactone Delta-isomerase ({{EC number|5.3.3.4}}) is an enzyme that catalyzes the chemical reaction

(S)-5-oxo-2,5-dihydrofuran-2-acetate 5-oxo-4,5-dihydrofuran-2-acetate

Hence, this enzyme has one substrate, (S)-5-oxo-2,5-dihydrofuran-2-acetate, and one product, 5-oxo-4,5-dihydrofuran-2-acetate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is 5-oxo-4,5-dihydrofuran-2-acetate Delta3-Delta2-isomerase. This enzyme is also called muconolactone isomerase. This enzyme participates in benzoate degradation via hydroxylation.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code {{PDB link|1MLI}}.

References

{{cite journal | vauthors = Ornston LN | title = The conversion of catechol and protocatechuate to beta-ketoadipate by Pseudomonas putida. 3. Enzymes of the catechol pathway | journal = The Journal of Biological Chemistry | volume = 241 | issue = 16 | pages = 3795–9 | date = August 1966 | pmid = 5330966 }}
{{cite journal | vauthors = Ornston LN | date = 1970 | title = Conversion of catechol and protocatechuate to beta-ketoadipate (Pseudomonas putida) | journal = Methods Enzymol. | volume = 17A | pages = 529–549 | doi=10.1016/0076-6879(71)17237-0}}

2 : EC 5.3.3|Enzymes of known structure

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。