| 词条 | Mucosa-associated lymphoid tissue |
| 释义 |
| Name = Mucosa-associated lymphoid tissue | Latin = | Image = | Caption = | Width = | Precursor = | System = Lymphatic system | Acronym = MALT | Artery = | Vein = | Nerve = | Lymph = }} The mucosa-associated lymphoid tissue (MALT), also called mucosa-associated lymphatic tissue, is a diffuse system of small concentrations of lymphoid tissue found in various submucosal membrane sites of the body, such as the gastrointestinal tract, oral passage, nasopharyngeal tract, thyroid, breast, lung, salivary glands, eye, and skin. MALT is populated by lymphocytes such as T cells and B cells, as well as plasma cells and macrophages, each of which is well situated to encounter antigens passing through the mucosal epithelium. In the case of intestinal MALT, M cells are also present, which sample antigen from the lumen and deliver it to the lymphoid tissue. There are three types of situations in which MALT is present- Tonsils, Appendix, Small Intestinal area CategorizationThe components of MALT are sometimes subdivided into the following:
It can be also distinguished by level of organization of the tissue:
Role in diseaseMALT plays a role in regulating mucosal immunity. It may be the site of lymphoma, usually non-Hodgkin lymphoma. A specific entity is the MALT lymphoma linked to Helicobacter pylori in the stomach. References1. ^{{cite journal |author1=Hong Liang |author2=Christophe Baudouin |author3=Antoine Labbe |author4=Luisa Riancho |author5=Françoise Brignole-Baudouin |year=2012 |title=Conjunctiva-associated lymphoid tissue (CALT) reactions to antiglaucoma prostaglandins with or without BAK-preservative in rabbit acute toxicity study |journal=PLoS One |volume=7 |issue=3 |page=e33913 |pmid=22442734 |pmc=3307783 |doi=10.1371/journal.pone.0033913}} 2. ^1 Gray's Anatomy, 38ed. p. 1442 ff. External links
1 : Lymphoid organ |
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